polyvinylpyrrolidone (pharm grade)
structural formula
formula: (c6h9no)n
ctfa nomenclature: pvp k30
cas no: 9003-39-8
characters:
in the form of off-white, free-flowing powder.
odorless or with a faint characteristic odor.
soluble in water and many organic solvents.
inert physiologically.
pecifications:
|
k17 |
k25 |
k30 |
k90 |
k90 (liquid) |
|
k value |
15-19 |
23-27 |
27-32 |
81-99 |
90-103 |
|
vinylpyrrolidone, % |
≤0.2 |
≤0.2 |
≤0.2 |
≤0.2 |
≤0.2 |
|
water, % |
≤5.0 |
≤5.0 |
≤5.0 |
≤5.0 |
79-81 |
|
sulfate ash, % |
≤0.1 |
≤0.1 |
≤0.1 |
≤0.1 |
≤0.1 |
|
nitrogen, % |
11.5-12.8 |
11.5-12.8 |
11.5-12.8 |
11.5-12.8 |
11.5-12.8 |
|
ph of 10% solution |
3.0-7.0 |
3.0-7.0 |
3.0-7.0 |
3.0-7.0 |
7.0-10.5 |
|
heavy metals(pb),ppm |
≤10 |
≤10 |
≤10 |
≤10 |
≤10 |
|
acetaldehyde, ppm |
≤500 |
≤500 |
≤500 |
≤500 |
≤500 |
|
hydrazine,ppm |
≤1 |
≤1 |
≤1 |
≤1 |
≤1 |
|
peroxides(as h2o2),ppm |
≤400 |
≤400 |
≤400 |
≤400 |
≤400 |
applications:
√ excellent pharmaceutical excipients.
√ granulation binders for tablets.
√ solubilizers and suspending agents for injections.
√ dispersants for dye and pigment in tablet and capsule coating.
√ stabilizers for enzymes and heat sensitive drugs.
√ coprecipitates for poorly soluble drugs.
√ lubricators and detoxifiers in ophthalmic solutions.
√ stabilizers for suspensions of all kinds of active substances.
√ viscosity adjustors, cohesive agents, stabilizers and protective colloids in oral liquid and other liquid formulations.
packing:
25kgs fiber drum and 150 kgs plastic drums for liquid.