rifabutin nature
melting point 169-171 ° c
storage condition amber vial, -20 ° c freezer, under inert atmosphere
solubility dmso:> 5 mg / ml
inchikey atebxhfbfrczma-vxtbvibxsa-n
rifabutin use and synthesis methods
fuchsine crystalline chemical powder. very soluble in chloroform, soluble in methanol, slightly soluble in ethanol, very slightly soluble in water. uv absorption maximum (methanol): 493, 315, 274, 238 nm.
use of rifamycin derivatives, anti-rifampicin-resistant tuberculosis strains. the required concentration is only 1/40 of rifampicin. toxicity less than rifampicin. japan will use it for the treatment of atypical m. tuberculosis infection. resistant to leprosy also effective. prevention of mycobacterium tuberculosis infection in aids patients.