((1r,4s)-2-azabicyclo[2.2.1]hept-5-en-3-one basic information
product name: ((1r,4s)-2-azabicyclo[2.2.1]hept-5-en-3-one
synonyms: (1r)-(-)-2-azabicyclo[2.2.1]hept-5-en-3-one;(1r,4s)-2-aza-bicyclo[2.2.1]hept-5-en-3-one;(-)-vince's lactam;(1r)-(-)-2-azabicyclo(2.2.1)hept-5-en-3- one, 98+% (99% ee/hplc);(-)-vince lactam;(1r)-(-)-2-azabicyclo[2.2.1]hept-5-en-3-one,98%,> 95%ee;(-)-2-azabicyclo[2.2.1]hept-5-en-3-one, > 95% ee;(1r)-(-)-2-azabicyclo[2.2.1]hept-5-en-3-one ,98%
cas: 79200-56-9
mf: c6h7no
mw: 109.13
einecs: 418-530-1
product categories: antiviral agents;chiral building blocks;lactams;organic building blocks;chiral reagents;heterocycles;intermediates;heterocycle-other series
mol file: 79200-56-9.mol
((1r,4s)-2-azabicyclo[2.2.1]hept-5-en-3-one structure
((1r,4s)-2-azabicyclo[2.2.1]hept-5-en-3-one chemical properties
melting point 94-97 °c(lit.)
form crystals or crystalline powder
color off-white to beige
inchikey ddufyknoxpzziw-uhnvwzdzsa-n
safety information
hazard codes xn
risk statements 22-41-43
safety statements 24-26-37/39
wgk germany 1
msds information
provider language
sigmaaldrich english
acros english
((1r,4s)-2-azabicyclo[2.2.1]hept-5-en-3-one usage and synthesis
chemical properties off-white to beige crystals or crystalline powder
uses abacavir intermediate. used as an intermediate in the synthesis of carbocyclic sugar amines, carbanucleosides, and carbocyclic dinucleotide analogues.
((1r,4s)-2-azabicyclo[2.2.1]hept-5-en-3-one preparation products and raw materials
raw materials etanol-->ethyl acetate-->tetrahydrofuran-->potassium carbonate-->ammonium hydroxide-->paraformaldehyde-->isopropyl ether-->tert-butyl methyl ether-->1,3-cyclopentadiene-->vinyl acetate-->lipase-->cyanogen bromide-->sodium p-toluenesulfonate-->10,11-dimethoxystrychnine
preparation products (1r,3s)-3-aminocyclopentanecarboxylic acid-->(1r,4s)-4-aminocyclopent-2-enecarboxylic acid