2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-n-phenylpentanamide basic information
product name: 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-n-phenylpentanamide
synonyms: m-4;2[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-pentanoic acid phenylamide;4-fluoro-alpha-(2-methyl-1-oxopropyl-gama-oxo)-n,beta-diphenylbenzene butaneamide;4-fluoro-alpha-[2-methyl-1-oxopropyl-gamma(3)-oxo]-n,beta-diphenylbenzene butane amide;4-fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-n,bata-diphenylbenzene butaneamide;4-fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-n, beta-diphenylbenzene butanamide;4-fluoro-alpha-[2-methyl-1-oxopropyl]-gamma-oxo-n,beta-diphenylbenzene butaneamide;4-(4-fluorophenyl)-2-isobutyryl-3-phenyl-4-oxo-n-phenyl-butanamide
cas: 125971-96-2
mf: c26h24fno3
mw: 417.47
einecs: 425-850-3
product categories: chemical intermediate for atorvastatin calcium;intermediatesofatorvastatin;(intermediate of atorvastatin);aromatices;intermediates & fine chemicals;pharmaceuticals;intermediates of atorvastatin
mol file: 125971-96-2.mol
2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-n-phenylpentanamide structure
2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-n-phenylpentanamide chemical properties
melting point 196-1980c
density 1.211
storage temp. -20°c freezer
cas database reference 125971-96-2(cas database reference)
safety information
msds information
2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-n-phenylpentanamide usage and synthesis
chemical properties white to off-white solid
uses an atorvastatin intermediate. atorvastatin is a selective, competitive hmg-coa reductase inhibitor. the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with hypercholesterolemia
2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-n-phenylpentanamide preparation products and raw materials
raw materials aniline-->benzaldehyde-->bromoethane-->ethylenediamine-->beta-alanine-->4-fluorobenzaldehyde-->5-(2-hydroxyethyl)-4-methylthiazole-->methyl isobutyrylacetate