4,4'-diaminodiphenylsulfone basic information
product name: 4,4'-diaminodiphenylsulfone
synonyms: sulfona-mae;sulphadione;timtec-bb sbb003168;p-aminophenyl sulfone;novophone;p,p'-sulfonyldianiline;bis(p-aminophenyl)sulfone;avlosulfon
cas: 80-08-0
mf: c12h12n2o2s
mw: 248.3
einecs: 201-248-4
product categories: pharmaceutical raw materials;aromatic hydrocarbons (substituted) & derivatives;diphenyl sulfones (for high-performance polymer research);functional materials;reagent for high-performance polymer research;intermediates & fine chemicals;pharmaceuticals;peptide synthesis/antibiotics
mol file: 80-08-0.mol
4,4'-diaminodiphenylsulfone structure
4,4'-diaminodiphenylsulfone chemical properties
melting point 175-177 °c(lit.)
storage temp. -20°c freezer
water solubility <0.1 g/100 ml at 20 ºc
merck 14,2822
brn 788055
stability: stable. combustible. incompatible with strong oxidizing agents.
cas database reference 80-08-0(cas database reference)
nist chemistry reference dapsone(80-08-0)
epa substance registry system benzenamine, 4,4'-sulfonylbis-(80-08-0)
safety information
hazard codes xn
risk statements 22
safety statements 22
ridadr 3249
wgk germany 1
rtecs by8925000
tsca yes
hazardclass 6.1(b)
packinggroup iii
hs code 29051620
hs code 29309070
hazardous substances data 80-08-0(hazardous substances data)
msds information
provider language
dapsonum english
sigmaaldrich english
acros english
alfa english
4,4'-diaminodiphenylsulfone usage and synthesis
chemical properties off -white crystalline solid
usage an antibacterial used in the treatment of dermatitis herpetiformis
usage antibacterial, leprostatic, dermatitis herpetiformis suppressant
usage 4,4'-diaminodiphenylsulfone be used for preparation polyimide and epoxy resin material.
definition chebi: a sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. it is active against a wide range of bacteria, but is mainly employed for its actions against mycobacteriu leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy.
general description odorless white or creamy white crystalline powder. slightly bitter taste.
air & water reactions sensitive to oxidation and light. insoluble in water.
reactivity profile 4,4'-diaminodiphenylsulfone can neutralize acids in exothermic reactions to form salts plus water. may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides. incompatible with strong oxidizing agents. also incompatible with epoxy resins under uncontrolled conditions .
fire hazard 4,4'-diaminodiphenylsulfone is probably combustible.
4,4'-diaminodiphenylsulfone preparation products and raw materials
preparation products acedapsone