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Henan Tianfu Chemical Co., Ltd.TIANFU-CHEM - Imatinib mesylate//file1.lookchem.com/300w\2010-5\4e83df59-0a87-45e8-988d-6b99161ce379.jpg
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TIANFU-CHEM - Imatinib mesylate CAS NO.220127-57-1

Min.Order Quantity:
1 Kilogram
Purity:
99.0%
Port:
SHANGHAI
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • Imatinib mesylateImatinib mesylate
  • 220127-57-1
  • C30H35N7O4S

Quick Details

  • ProName: TIANFU-CHEM - Imatinib mesylate
  • CasNo: 220127-57-1
  • Molecular Formula: C30H35N7O4S
  • Appearance: Off-White Solid
  • Application: Organic synthesis
  • DeliveryTime: PROMPT
  • PackAge: IN 25kg drums
  • Port: SHANGHAI
  • ProductionCapacity: 10 Metric Ton/Month
  • Purity: 99.0%
  • Storage: In Room Temperature
  • Transportation: As per the MSDS
  • LimitNum: 1 Kilogram
  • Heavy metal: N/A
  • Grade: Industrial Grade,Food Grade,Pharma Gra...
  • N/A: N/A

Superiority

imatinib mesylate basic information
a small-molecule inhibitor
product name: imatinib mesylate
synonyms: glivec;gleevec;imatinib methanesulfonate;cgp-57148b;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;sti-571;imatinib base(ima-3)
cas: 220127-57-1
mf: c30h35n7o4s
mw: 589.71
einecs:
product categories: active pharmaceutical ingredients;intermediates & fine chemicals;pharmaceuticals;tyrosine kinase inhibitors;aromatics;heterocycles;api;glivec, cgp-57148b, sti-571;antineoplastic;anti-cancer&immunity;inhibitors
mol file: 220127-57-1.mol
imatinib mesylate structure

Details

imatinib mesylate chemical properties
mp 214-224°c
storage temp. -20°c freezer
cas database reference 220127-57-1(cas database reference)
safety information
hazard codes xn
risk statements 22
hazardous substances data 220127-57-1(hazardous substances data)
msds information
imatinib mesylate usage and synthesis
a small-molecule inhibitor imatinib mesylate (also called gleevec) is a small-molecule inhibitor of the fusion protein bcr-abl, the causal agent in chronic myelogenous leukemia.
as an inhibitor of pdgfr, imatinib mesylate appears to have utility in the treatment of a variety of dermatological diseases. imatinib has been reported to be an effective treatment for fip1l1-pdgfralpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.
chemical properties off-white solid
usage a tyrosine kinase inhibitor. highly specific for bcr-abl, the enzyme associated with chronic myelogenous leukemia (cml) and certain forms of acute lymphoblastic leukemia (all)
usage imatinib mesylate is orally bioavailability mesylate salt of imatinib, which is a multi-target inhibitor of v-abl, c-kit and pdgfr with ic50 of 0.6 μm, 0.1 μm and 0.1 μm, respectively. imatinib also known as gleevec, glivec, cgp-57148b, sti-571 & imatinib
usage imatinib mesylate (sti571) is an orally bioavailability mesylate salt of imatinib, which is a multi-target inhibitor of v-abl, c-kit and pdgfr with ic50 of 0.6 μm, 0.1 μm and 0.1 μm, respectively.
usage echinocandin antifungal, active against infections with aspergillus and candida, inhibits cell wall synthesis

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