TIANFU-CHEM - Triptorelin CAS NO.57773-63-4

Min.Order Quantity:: 1 Kilogram

Purity:: 99.0%

Port:: SHANGHAI

Payment Terms:: L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

Triptorelin
57773-63-4
C64H82N18O13

Quick Details

ProName: TIANFU-CHEM - Triptorelin
CasNo: 57773-63-4
Molecular Formula: C64H82N18O13
Appearance: Solid
Application: Organic synthesis
DeliveryTime: PROMPT
PackAge: IN 25kg drums
Port: SHANGHAI
ProductionCapacity: 10 Metric Ton/Month
Purity: 99.0%
Storage: In Room Temperature
Transportation: As per the MSDS
LimitNum: 1 Kilogram
Heavy metal: N/A
Grade: Industrial Grade,Food Grade,Pharma Gra...
N/A: N/A

Superiority

our company engages in sodium tripolyphosphate (stpp) and sodium hexametabphosphate (shmp) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals imp&exp trading business. the company is located in zhengzhou high-tech development zone with import and export license. we passed iso 9001:2008 in 2009, and won "high-tech enterprise" by provincial government in 2013. our stpp and shmp has reached an annual output of 30000 tons and has successfully passed sgs, ciq audits on many occasions.

in 2011 we entered the fine chemical market of noble metal catalyst ,organic phosphine ligands and oled intermediates.with the joint efforts of our senior experts and professional technicians, tianfu has developed more than 500 compounds, which are widely used in the fields of production and life science. the objective of the company is to put quality first and put our customer’s needs first - the satisfaction of our customers is the company's ultimate goal. improving product quality and service level is our responsibility, and creating more value for our customer’s is our purpose. we are constantly striving to make henan tianfu a leading chemical supplier, and hope to create a better future with you.

Details

triptorelin basic information

antineoplastic drug

product name:	triptorelin
synonyms:	pglu-his-trp-ser-tyr-d-trp-leu-arg-pro-gly-nh2;pyroglu-his-trp-ser-tyr-d-trp-leu-arg-pro-gly nh2;pyr-his-trp-ser-tyr-d-trp-leu-arg-pro-gly-nh2;pyr-his-trp-ser-tyr-d-trp-leu-arg-pro-gly-nh2 pamoate salt;triptorelin pamoate;triptorelin acetate;triptorelin amide;triptorelin, [dtrp6]-lh-rh, amide
cas:	57773-63-4
mf:	c64h82n18o13
mw:	1311.45
einecs:
product categories:	amino acid derivatives;peptide
mol file:	57773-63-4.mol

triptorelin chemical properties

storage temp.	−20°c
form	powder
cas database reference	57773-63-4(cas database reference)

safety information

hazard codes	t
risk statements	60
safety statements	53-22-36/37/39-45
wgk germany	3

msds information

provider	language
sigmaaldrich	english

triptorelin usage and synthesis

antineoplastic drug

the active ingredient of triptorelin is a synthetic gonadotropin-releasing hormone (gnrh) analogue, which is also known as decapeptyl, diphereline, triptorelin acetate, gonadorelin. it is an antineoplastic drug, whose pharmacological effects are same with goserelin, buserelin, and its structure is modified by natural molecular structure of the sixth l-glycine that is replaced by d-tryptophan to promote efficiency and prolong the plasmic half-life time, as well as enhance drug efficacy. after intramuscular injection, it initially stimulates the pituitary gland to release luteinizing growth hormone (lh) and follicle-stimulating hormone (fsh). when the pituitary over a long period of stimulation will be into the refractory period, that reduced the release of gonadotropin, leading to sex hormones reduction to castrate levels. these effects are reversible. subcutaneous administration is rapidly absorbed, and tmax is 15min, and the effect is maximum at 1h. the intramuscular injection of sustained release formulations can maintain the efficacy reaching 28d or more. it clinically uses for the treatment of endometriosis, hormone-dependent prostate cancer, breast cancer, precocious puberty, as well as it may also be used as assisted reproductive technology. the main side effects of triptorelin are as follows: in the early stage of treatment of male, it can cause urinary disorders, breast swelling and pain, bone pain, and it may also cause hot flashes, loss of libido and impotence. it rarely cause gynecomastia, testicular atrophy, and sleep disorders. in the first week of treatment for children, girls will occur small amount of vaginal bleeding, which can be corrected by short-term additional therapy. during the treatment of women, hot flashes, bleeding or bleeding spots, vaginal dryness, headaches and weakness can occur. it can cause abdominal and (or) pelvic pain when it uses combination with gonadotropin. since the concentration of estrogen reduces to the level of post-menopause, it can cause slight loss of trabecular bone matrix. generally, after cessation of treatment six to nine months the adverse reations can return to normal. there may be irreversible amenorrhea after treatment in patients with endometriosis.
the above information is edited by the chemicalbook of kui ming.

usage

promoting ovulation

triptorelin preparation products and raw materials

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