Welcome to LookChem.com Sign In|Join Free
  • or
Henan Tianfu Chemical Co., Ltd.TIANFUCHEM--70356-03-5 --High purity Cefaclor monohydrate factory price//file1.lookchem.com/300w/synthetic/2022-01-24-03/70fc57b3-57f0-4ffc-a886-2246fb828724.png
qq

Communicate with Supplier:

Mr. Anson
Mr. Anson: What can I do for you?

TIANFUCHEM--70356-03-5 --High purity Cefaclor monohydrate factory price CAS NO.70356-03-5

FOB Price:
USD 2,000.00-2,000.00 /Metric Ton Get Latest Price
Min.Order Quantity:
1 Metric Ton
Purity:
99%
Port:
China Main Port
Payment Terms:
L/C,T/T

Add to Inquiry Cart

Product Details

Keywords

  • TIANFUCHEM--70356-03-5
  • High purity Cefaclor monohydrate
  • Cefaclor monohydrate factory price

Quick Details

  • ProName: TIANFUCHEM--70356-03-5 --High purity C...
  • CasNo: 70356-03-5
  • Molecular Formula: C15H16ClN3O5S
  • Appearance: White Powder
  • Application: API,Pharmaceutical intermediates
  • DeliveryTime: In Stock
  • PackAge: 25KGS/Drum
  • Port: China Main Port
  • ProductionCapacity: 1000 Metric Ton/Day
  • Purity: 99%
  • Storage: Room temperature
  • Transportation: BY SEA
  • LimitNum: 1 Metric Ton
  • Heavy metal: N/A
  • Grade: Industrial Grade,Food Grade
  • Transportation: N/A

Superiority

tianfuchem--70356-03-5 --high purity cefaclor monohydrate factory price

our company was built in 2009 with an iso certificate.in the past 10 years,

we have grown up as a famous fine chemicals supplier in china
and we had established stable business
relationships with samsung,lg,merck,thermo fisher scientific and so on.
our main business covers the fields below:
1.noble metal catalysts (pt.pd...)
2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)
3.oled intermediates (fluorene,carbazole,boric acid...)
4.pharmaceutical intermediates
about us
1.more than 10 years chemical exporting experience
we have produced chemical more than fifteen years., 80% products are for export .
more than 10 years chemical exporting experience. good and stabilized factory price.
2.strict quality control system
3.supply sample
before order , we can send the sample for your testing . we ensure the quality is the same as bulk quantity .
our advantage:
q1:can i get the free sample
a: yes, we can supply the free sample, but the shipping cost be paid by our customers.
q2: how to start orders or make payments
a: proforma invoice will be sent first after confirmation of order, enclosed our bank information.
payment by t/t, or paypal or l/c.
q3: how to confirm the product quality before placing orders
a:you can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
you can send us your product specifications and requests,we will manufacture the products according to your requests.
q4:what’s your moq
a:usually according you demand.
q5: how about delivery leadtime
a:delivery lead time: as soon as possible. (chinese holiday not included)
q6:is there a discount
a:different quantity has different discount.
q7: how to contact us
a:you can chat with us by trademanager,email,whatsapp,wechat.
you can choose your interested products and send inquiry to us.
you can dial our telephone directly, you will get our reply.

Details

tianfuchem--70356-03-5 --high purity cefaclor monohydrate factory price
our company was built in 2009 with an iso certificate.in the past 10 years,
we have grown up as a famous fine chemicals supplier in china
and we had established stable business
relationships with samsung,lg,merck,thermo fisher scientific and so on.
details
cefaclor monohydrate
english synonyms: (7r) -3-chloro-7 - [[(r) -aminophenylacetyl] amino] cepham-3- ene-4-carboxylic acid sodium salt; 2-amino-2-phenyl-acetyl] amino] -3-chloro-8-keto-5-thia-1-azabicyclo [4.2.0] oct- 2-amino-2-phenylacetyl] amino] -3-chloro-8-oxo-5-thia-1-azabicyclo [4.2.0] oct- 2-carboxylic acid hydrate; (6r, 7r) -7 - [[(2r) -2-azanyl-2-phenyl- ethanoyl] amino] -3-chloro-8-oxo-5-thia-1-azabicyclo [4.2 oct-2-ene-2-carboxylic acid hydrate; cefaclor (400 mg) -2-amino-2-phenylacetyl] amino] -3-chloro-8-oxo-, hydrate (1: 1), (6r, 7r) -; cefaclor hydrate
cas number: 70356-03-5
molecular formula: c15h16cln3o5s
molecular weight: 385.82
einecs number: 258-909-5
related categories: heterocycles; antipyretic and analgesic apis; pharmaceutical intermediates; small molecules inhibitors; chiral reagents; intermediates & fine chemicals; pharmaceuticals; sulfur & selenium compounds;
mol file: 70356-03-5.mol
cefaclor (a water)
cefaclor (a water) properties
melting point> 180 ° c (dec.)
storage conditions -20 c freezer
cas database 70356-03-5 (cas database reference)
cefaclor (a water) use and synthesis methods
chemical white or almost white crystalline powder. dissolved in water, almost insoluble in methanol, chloroform or benzene. stable at ph = 2.5-4.5. uv absorption maximum (ph = 7 buffer): 265 nm (ε6800).
use the first generation cephalosporin antibiotics, antibacterial properties and cefazolin approximation. clinical mainly for urinary tract infections, respiratory infections, skin and soft tissue infections, ent and other infections, better effect.
use is a cephalosporin antibiotic drugs, mainly for urinary tract infections and respiratory infections
production methods to penicillin g as raw material. the first use of p-nitrobenzyl on penicillin g carboxyl protection, and then with hydrogen peroxide or peracetic acid oxidation to sulfoxide. under the action of n-chlorosuccinimide or n-chlorophthalide, chlorination and ring expansion. oxidation after the first reduction, so that the formation of hydroxyl 3. then the first three under phosphorus trichloride, the three into chlorinated; then phosphorus pentachloride and pyridine, followed by alcoholysis 7 position to form the free amino hydrochloride, 7-amino-3-chloro -3-cephem-4-carboxylate hydrochloride. the solution was dissolved in tetrahydrofuran and methanol, 5% palladium-carbon in ethanol was added and hydrogenated at room temperature under a hydrogen pressure of 0.35 mpa for 45 min. filter, filter cake with tetrahydrofuran and water. solvent was evaporated to dryness. the residue was dissolved in a mixture of water and ethyl acetate and the ph value was adjusted to 3 to precipitate a solid which was filtered and soaked in acetone and then dried to give 7-amino-3-chloro-3-cephem-4-carboxylic acid . this was dissolved in acetonitrile and n, o-bis (trimethylsilyl) acetamide was added under stirring at room temperature to form a soluble bis-silyl ester. cool to 0 ° c and slowly add sodium salt of methyl 3- (β-carboxybenzylamine) crotonate and methyl chloroformate in acetonitrile in the presence of two drops of n, n-dimethylbenzylamine . the mixture was further stirred in an ice bath for 2 h, methanol was added and insoluble materials were removed by filtration. then add water, adjust ph value to 1.5, and then adjusted to 4.5 with triethylamine. stirring 1h on a water bath, precipitating the precipitated crystalline precipitate, washing with acetonitrile and drying in vacuo to give cefaclor.
the previously obtained hydrochloride of the free amino group can be reacted with azidophenacid directly, and then cefaclor can be obtained by hydrogenolysis, the reaction of which is relatively simple.
our main business covers the fields below:
1.noble metal catalysts (pt.pd...)
2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)
3.oled intermediates (fluorene,carbazole,boric acid...)
4.pharmaceutical intermediates
packing:
about us
1.more than 10 years chemical exporting experience
we have produced chemical more than fifteen years., 80% products are for export .
more than 10 years chemical exporting experience. good and stabilized factory price.
2.strict quality control system
3.supply sample
before order , we can send the sample for your testing . we ensure the quality is the same as bulk quantity .
delivery:
our advantage:
q1:can i get the free sample
a: yes, we can supply the free sample, but the shipping cost be paid by our customers.
q2: how to start orders or make payments
a: proforma invoice will be sent first after confirmation of order, enclosed our bank information.
payment by t/t, or paypal or l/c.
q3: how to confirm the product quality before placing orders
a:you can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
you can send us your product specifications and requests,we will manufacture the products according to your requests.
q4:what’s your moq
a:usually according you demand.
q5: how about delivery leadtime
a:delivery lead time: as soon as possible. (chinese holiday not included)
q6:is there a discount
a:different quantity has different discount.
q7: how to contact us
a:you can chat with us by trademanager,email,whatsapp,wechat.
you can choose your interested products and send inquiry to us.
you can dial our telephone directly, you will get our reply.
our factory
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)