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HENAN SUNLAKE ENTERPRISE CORPORATIONbuy 2627-69-2 AICAR(Acadesine)with best price//file1.lookchem.com/cas/reactions/2021/06/01/38255.png
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buy 2627-69-2 AICAR(Acadesine)with best price CAS NO.2627-69-2

Min.Order Quantity:
1 Kilogram
Purity:
99.0%
Port:
Any Chinese main ports
Payment Terms:
L/C,D/A,D/P,T/T,Other

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  • supplier of AICAR(Acadesine)
  • buy 2627-69-2 AICAR(Acadesine)with best price
  • Offer 2627-69-2 AICAR(Acadesine) CAS NO.2627-69-2

Quick Details

  • ProName: buy 2627-69-2 AICAR(Acadesine)with bes...
  • CasNo: 2627-69-2
  • Molecular Formula: C9H14N4O5
  • Appearance: white crystalline powder
  • Application: 1>2627-69-2 2>AICAR is a nucleoside a...
  • DeliveryTime: Within 7 working days since received y...
  • PackAge: 1g;5g;10g;25g;50g;100g;500g;1KG;5KG,25...
  • Port: Any Chinese main ports
  • ProductionCapacity: 100 Kilogram/Quarter
  • Purity: 99.0%
  • Storage: 2-8, cold storage, to avoid light stor...
  • Transportation: BY SEA /BY AIR /BY COURIER
  • LimitNum: 1 Kilogram
  • PackAge: Aluminum foil bag fluoride bottle

Superiority

1.high purity with hplc & nmr chart;
2.99% purity with low price;
3.direct manufacturer;
4.specilized in hard-to-find chemicals.

cbnumber: cb1675294
chemical name: aicar

Details

cbnumber: cb1675294
chemical name: aicar

aicar basic information

adenosine regulating agents
product name: aicar
synonyms: acadesine;aicar;aica-riboside;ampk;5-aminoimidazole-4-carboxamide-1-beta-riboside;5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside;5-aminoimidazole-4-carboxamide 1-beta-d-ribofuranoside;z-riboside
cas: 2627-69-2
mf: c9h14n4o5
mw: 258.23
einecs: 220-097-5
product categories: bases & related reagents;carbohydrates & derivatives;nucleotides;protein kinase;arasine;cardiovascular apis;pi3k/akt/mtor
mol file: 2627-69-2.mol
aicar structure
aicar chemical properties
mp 214-215 °c
storage temp. −20°c
solubility h2o: >10 mg/ml
form powder
color tan
cas database reference 2627-69-2(cas database reference)
epa substance registry system 1h-imidazole-4-carboxamide, 5-amino-1-.beta.-d-ribofuranosyl- (2627-69-2)
safety information
hazard codes xi,t
risk statements 36/37/38-61
safety statements 26-36-45-53
wgk germany 3
msds information
provider language
sigmaaldrich english
aicar usage and synthesis
adenosine regulating agents acadesine is the prototype of a new class of compounds termed adenosine regulating agents. acadesine is a purine nucleosid analogue that enters the myocyte and is immediately phosphorylated to zmp (aica ribotide), which is further metabolised to inosine mono-phosphate (an intermediate in the synthesis ofadenosine triphosphate (atp) and guanosine triphos-phate).
claims that acadesine may serve as a substrate for atp synthesis and result in repletion of myocardial atp were supported by some studies and refuted by others. because acadesine may be a precursor in the synthesis of myocardial atp it was proposed as a possible agent of myocardial protection during ischaemia, particularly because myocardial atp depletion has been linked to cell death.
chemical properties solid
usage glucose uptake stimulant; ampk activator
usage aicar is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of atp breakdown. adenosine-regulating agents (aras) hav e been recognized for therapeutic potential in myocardial ischemia. cardioprotective.
biological activity cell-permeable, allosteric activator of amp-activated protein kinase (ampk). augments proliferation, differentiation and mineralization of osteoblastic mc3t3-ei cells and attenuates psychosine-induced expression of proinflammatory cytokines and inos in astrocytes.

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