1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

Serious eye damage, Category 1

Skin sensitization, Category 1

Acute toxicity - Inhalation, Category 2

Specific target organ toxicity – single exposure, Category 3

Carcinogenicity, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Danger
Hazard statement(s)	H318 Causes serious eye damage H317 May cause an allergic skin reaction H330 Fatal if inhaled H335 May cause respiratory irritation H351 Suspected of causing cancer H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s)
Prevention	P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment.
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER/doctor/… P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label). P312 Call a POISON CENTER/doctor/…if you feel unwell. P308+P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

In case of eye contact

Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.

If swallowed

Rinse mouth. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

SYMPTOMS: Symptoms of exposure to this compound include dermatitis and gastrointestinal, skin and upper respiratory tract irritation. ACUTE/CHRONIC HAZARDS: This compound is a positive animal carcinogen. When heated to decomposition it emits toxic fumes of chloride ion, NOx and cyanide ion.

4.3 Indication of immediate medical attention and special treatment needed, if necessary

1. Wash off dermal contamination with soap and water. Remove contamination of the eyes by flushing with copious amounts of water. If irritation persists, specialized medical care should be obtained. /Substituted benzenes/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Fire Extinguishing Media: CO2, foam, dry chemical or water.

5.2 Specific hazards arising from the chemical

Literature sources indicate that this compound is nonflammable.

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: chemical protection suit and protective gloves. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Solid spillage should be picked up with an industrial vacuum cleaner and disposed of in accordance with local regulations.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access.Keep in cool, dry, ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Thermally stable at ambient temperatures. Stable to u.v. light in aqueous media and in crystalline state. Stable in acidic and moderately alkaline aqueous solutions; slow hydrolysis at pH >9.

10.3 Possibility of hazardous reactions

Chlorothalonil is non-flammable and non-explosive.CHLOROTHALONIL is stable in neutral or acidic aqueous media. May react violently with strong oxidizing acids [Farm Chemicals Handbook]. Incompatible with other oxidizing agents such as peroxides and epoxides. Breaks down slowly in basic aqueous media (half-life 38.1 days at pH 9). [Farm Chemicals Handbook].

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Cyanides

10.6 Hazardous decomposition products

May decompose at high temp to emit hydrogen chloride.

11.Toxicological information

Acute toxicity

• Oral: LD50 Mouse oral 3700 mg/kg
• Inhalation: LC50 Rat inhalation 310 mg/cu m/1hr
• Dermal: LD50 Rabbit (albino) percutaneous >5000 mg/kg

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Group B2 Probable Human Carcinogen

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

• Toxicity to fish: LC50; Species: /Oncorhynchus mykiss/ (Rainbow trout); Concentration: 76 ug/L for 96 hr /Technical chlorothalonil; conditions of bioassay not specified
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea) age <24 hr; Conditions: static; Concentration: 70 ppb for 48 hr (95% confidence limit: 34.2-143 ppb); Effect: intoxication, immobilization) /96% AI formulated product
• Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green algae); Conditions: static; Concentration: 190 ppb/120 hr (95% confidence limit: 180-210 ppb); Effect: decreased population abundance /97.9% AI formulated product
• Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: In an aerobic grab sample study, 60.5% chlorothalonil (initial concentration of 38 ppm) remained in an alluvial silty loam (25°C and pH 6.4) after 7 days(1). At an initial concentration of 40 ppm, 67.5% (20°C) and 45.0% (25°C) chlorothalonil remained after 7 days in an alluvial silty loam (pH 6.4) held at a 60% moisture capacity(1). In the same soil held at moisture capacities of 100, 60, 40, and 20%, the amount of chlorothalonil (initial concentration of 40 ppm) remaining was determined to be 85, 22, 45, and 65%, respectively, after 7 days. Chlorothalonil biodegraded mainly through dechlorination and partly by substitution reaction yielding the biodegradation products: isophthalonitrile, mono-, di- and tri-chlorinated isophthalonitriles, 2,5,6-trichloro-4-hydroxyisophthalonitrile and 2,5,6-trichloro-4-methoxyisophthalonitrile(1). Aerobic biodegradation half-lives of chlorothalonil in four different soils were reported as 10, 10, 15 and 40 days(2). After 60 days the metabolite 2,5,6-trichloro-4-hydroxyisophtalonitrile was present at up to 32% of the initially applied amount; the metabolite 3-cyano-2,4,5,6-tetrachlorobenzamide was present at up to about 7% at both days 7 and 16 of the study. Aerobic aquatic half-lives of chlorothalonil typically range from 2 to 200 hours(2). Other reported metabolites are 1,3-dicarbamoyl-2,4,5,6-tetrachlorobenzene, 1-carbamoyl-3-cyano-4-hydroxy-2,5,6-trichlorobenzene, 2,4,6-trichloro-4-(methylthio)isophthalonitrile and pentachloronitrobenzene(3).

12.3 Bioaccumulative potential

Bioconcentration factors of 75 (edible) and 264 (whole body) were measured for chlorothalonil in bluegill sunfish(1). BCF values of 9.4 (edible) and 16 (whole body) were reported for catfish(1). Carp exposed to 3 ug/L chlorothalonil over a 6 week incubation period had reported maximum BCF values of 125 (2). A BCF of 264 was determined in bluegill (Lepomis macrochirus) exposed for 28 days(3). According to a classification scheme(4), these BCF values suggest bioconcentration in aquatic organisms can be low to high(SRC). Chlorothalonil BAFs wet weight and lipid based in zooplankton from three lakes in southern Ontario, Canada were 14-1500 and 140-190,000, respectively; samples were collected in 2003 and 2004(5).

12.4 Mobility in soil

A Koc value of 1800 has been determined based on adsorption isotherms of chlorothalonil on 3 black soils and 1 clay mineral, Na-bentonite soil(1). Other reported Koc values are 1300 to 14,000(2). Laboratory batch equilibrium studies with four soils showed chlorothalonil to possess limited mobility in silty clay loam, silt, sandy loam, and sand with calculated Koc values were 1400, 7000, 1100, and 900, respectively(3). According to a classification scheme(4), these Koc values suggest the mobility of chlorothalonil in soils will be low to immobile(SRC). The Koc of sediment from recycling ponds was 2270 to 2450(5).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

14.2 UN Proper Shipping Name

14.3 Transport hazard class(es)

14.4 Packing group, if applicable

14.5 Environmental hazards

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

16.Other information

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.