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1002356-02-6

1-(3-bromophenyl)-2,2-difluoroethanone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1002356-02-6 Structure

  • Basic information

    1. Product Name: 1-(3-bromophenyl)-2,2-difluoroethanone
    2. Synonyms: 1-(3-bromophenyl)-2,2-difluoroethanone
    3. CAS NO:1002356-02-6
    4. Molecular Formula:
    5. Molecular Weight: 235.028
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1002356-02-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(3-bromophenyl)-2,2-difluoroethanone(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(3-bromophenyl)-2,2-difluoroethanone(1002356-02-6)
    11. EPA Substance Registry System: 1-(3-bromophenyl)-2,2-difluoroethanone(1002356-02-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1002356-02-6(Hazardous Substances Data)

1002356-02-6 Usage

Chemical Family

Fluorinated ketones

Structure

Presence of a bromine atom attached to a phenyl group and two fluorine atoms attached to a carbon atom in a ketone functional group

Usage

Commonly used in organic synthesis and medicinal chemistry

Role

Building block for the preparation of various biologically active molecules

Uniqueness

Its unique structure and reactivity make it a valuable intermediate

Applications

Production of pharmaceuticals, agrochemicals, and other fine chemicals

Interest

Subject of interest for researchers and manufacturers in the chemical industry

Check Digit Verification of cas no

The CAS Registry Mumber 1002356-02-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,2,3,5 and 6 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1002356-02:
(9*1)+(8*0)+(7*0)+(6*2)+(5*3)+(4*5)+(3*6)+(2*0)+(1*2)=76
76 % 10 = 6
So 1002356-02-6 is a valid CAS Registry Number.

1002356-02-6Relevant articles and documents

Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent

Miele, Margherita,Citarella, Andrea,Micale, Nicola,Holzer, Wolfgang,Pace, Vittorio

supporting information, p. 8261 - 8265 (2019/10/16)

The homologation of Weinreb amides into difluoromethylketones with a formal nucleophilic CHF2 transfer agent is reported. Activating TMSCHF2 with potassium tert-amylate enables a convenient access to the difluorinated homologation re

Catalytic Enantioselective Synthesis of Highly Functionalized Difluoromethylated Cyclopropanes

Bos, Maxence,Huang, Wei-Sheng,Poisson, Thomas,Pannecoucke, Xavier,Charette, André B.,Jubault, Philippe

supporting information, p. 13319 - 13323 (2017/10/17)

The first catalytic asymmetric synthesis of highly functionalized difluoromethylated cyclopropanes is described. The method, based on a rhodium-catalyzed cyclopropanation of difluoromethylated olefins, gives access to a broad range of cyclopropanes bearing ester, ketone, or nitro functional groups. By using Rh2((S)-BTPCP)4 as a catalyst, the corresponding products were obtained in high yields and high diastereo- and enantioselectivities (up 20:1 d.r. and 99 % ee). This methodology allowed preparation of enantioenriched difluoromethylcyclopropanes for the first time.

Oxazine Derivatives and their Use in the Treatment of Neurological Disorders

-

Page/Page column 39, (2012/07/14)

The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their medical use and to medicaments comprising them.

Oxazine derivatives and their use in the treatment of neurological disorders

-

, (2013/02/28)

The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their medical use and to medicaments comprising them.

OXAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS

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Page/Page column 38, (2011/02/18)

The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their medical use and to medicaments comprising them.

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