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4-chloro-2-cyclopropylpyrimidine is a chlorinated cyclopropylpyrimidine derivative with the molecular formula C7H7ClN2. It is a key building block in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of anticancer and antifungal agents. Known for its reactivity and versatility in organic synthesis, 4-chloro-2-cyclopropylpyrimidine is a valuable asset in medicinal chemistry and drug discovery. However, due to its potential hazards and toxicological properties, it requires careful handling.

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  • 1044771-74-5 Structure
  • Basic information

    1. Product Name: 4-chloro-2-cyclopropylpyrimidine
    2. Synonyms: 4-chloro-2-cyclopropylpyrimidine
    3. CAS NO:1044771-74-5
    4. Molecular Formula: C7H7ClN2
    5. Molecular Weight: 154.59688
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1044771-74-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-chloro-2-cyclopropylpyrimidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-chloro-2-cyclopropylpyrimidine(1044771-74-5)
    11. EPA Substance Registry System: 4-chloro-2-cyclopropylpyrimidine(1044771-74-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1044771-74-5(Hazardous Substances Data)

1044771-74-5 Usage

Uses

Used in Pharmaceutical Industry:
4-chloro-2-cyclopropylpyrimidine is used as an intermediate in the synthesis of various biologically active molecules for the development of pharmaceuticals. Its reactivity and versatility make it a valuable compound in creating new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
4-chloro-2-cyclopropylpyrimidine is used as a key building block in the production of agrochemicals, specifically in the development of antifungal agents. Its role in creating effective compounds against fungal infections contributes to the protection and enhancement of crop yields.
Used in Medicinal Chemistry and Drug Discovery:
4-chloro-2-cyclopropylpyrimidine is utilized as a valuable compound in the field of medicinal chemistry and drug discovery. Its potential in the development of anticancer agents highlights its importance in creating innovative treatments for various types of cancer.
Used in Organic Synthesis:
4-chloro-2-cyclopropylpyrimidine is employed in organic synthesis due to its reactivity and versatility. This allows for the creation of a wide range of chemical compounds with diverse applications across various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 1044771-74-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,4,7,7 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1044771-74:
(9*1)+(8*0)+(7*4)+(6*4)+(5*7)+(4*7)+(3*1)+(2*7)+(1*4)=145
145 % 10 = 5
So 1044771-74-5 is a valid CAS Registry Number.

1044771-74-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-2-cyclopropylpyrimidine

1.2 Other means of identification

Product number -
Other names 4-chloro-2-cyclopropylpyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1044771-74-5 SDS

1044771-74-5Downstream Products

1044771-74-5Relevant articles and documents

PURINES AND METHODS OF THEIR USE

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Page/Page column 85, (2021/12/28)

Disclosed are compounds useful in the treatment of neurological disorders. The compounds described herein, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological diseases.

17α-HYDROXYLASE/C17,20-LYASE INHIBITORS

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Page/Page column 88, (2012/11/13)

The present invention provides compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4, R5 and R6 are as defined herein. The compounds of the present invention have been found to be useful as 17α-hydroxylase/C17,20-lyase inhibitors.

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