117519-13-8 Usage
Uses
Used in Pharmaceutical Industry:
6-chloro-2-(trifluoromethyl)pyridin-3-amine is used as a key intermediate in the synthesis of new drugs. Its unique structure allows for the development of pharmaceuticals with novel mechanisms of action and improved therapeutic profiles.
Used in Agrochemical Industry:
In the agrochemical sector, 6-chloro-2-(trifluoromethyl)pyridin-3-amine serves as an intermediate for the production of agricultural products, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness and selectivity, leading to better crop protection and yield.
Used in Materials Science:
6-chloro-2-(trifluoromethyl)pyridin-3-amine is utilized as a building block in the synthesis of complex organic molecules for various applications in materials science. Its unique properties can contribute to the development of advanced materials with improved performance characteristics.
Used in Specialty Chemicals:
6-chloro-2-(trifluoromethyl)pyridin-3-amine also finds applications in the specialty chemicals industry, where it is employed in the production of high-value chemical products. Its unique structure and properties can be leveraged to create innovative and specialized chemical products for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 117519-13-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,5,1 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 117519-13:
(8*1)+(7*1)+(6*7)+(5*5)+(4*1)+(3*9)+(2*1)+(1*3)=118
118 % 10 = 8
So 117519-13-8 is a valid CAS Registry Number.
117519-13-8Relevant articles and documents
PYRROLO CARBOXAMIDES AS MODULATORS OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (ROR?, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES
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, (2013/06/27)
The invention provides modulators for the orphan nuclear receptor ROR? and methods for treating ROR? mediated diseases by administrating these novel ROR? modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo carboxamide compounds of Formula (1) and the enantiomers, diastereomers, N-oxides, tautomers, solvates and pharmaceutically acceptable salts thereof.
Electrophilic trifluoromethylation of arenes and N-heteroarenes using hypervalent iodine reagents
Wiehn, Matthias S.,Vinogradova, Ekaterina V.,Togni, Antonio
experimental part, p. 951 - 957 (2010/10/02)
The reaction of hypervalent iodine trifluoromethylating reagents with a variety of arenes and N-heteroarenes gives access to the corresponding trifluoromethylated compounds. In comparative studies, 1-trifluoromethyl-1,3- dihydro-3,3-dimethyl-1,2-benziodoxole (2) proved to be the superior to 1-trifluoromethyl-1,2-benziodoxol-3-(1H)-one (1) for the direct aromatic trifluoromethylation. Depending on the individual substrates, additives such as zinc bis(trifluoromethylsulfonyl)imide or tris(trimethylsilyl)silyl chloride proved helpful in promoting the reactions. In the case of nitrogen heterocycles a pronounced tendency for the incorporation of the trifluoromethyl group at the position adjacent to nitrogen was observed.