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Methyl 4-bromoquinoline-8-carboxylate is a chemical compound with the molecular formula C12H8BrNO2. It is an ester derivative of 4-bromoquinoline-8-carboxylic acid, characterized by its potential biological activities and versatile nature in the synthesis of various biologically active compounds. methyl 4-bromoquinoline-8-carboxylate is commonly utilized in organic synthesis and serves as an intermediate in the production of pharmaceuticals and agrochemicals, making it a valuable asset in the field of medicinal chemistry.

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  • 132664-48-3 Structure
  • Basic information

    1. Product Name: methyl 4-bromoquinoline-8-carboxylate
    2. Synonyms: methyl 4-bromoquinoline-8-carboxylate
    3. CAS NO:132664-48-3
    4. Molecular Formula: C11H8BrNO2
    5. Molecular Weight: 266.09072
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 132664-48-3.mol
  • Chemical Properties

    1. Melting Point: 55-56 °C(Solv: hexane (110-54-3))
    2. Boiling Point: 368.7±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.557±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. PKA: 1.57±0.30(Predicted)
    10. CAS DataBase Reference: methyl 4-bromoquinoline-8-carboxylate(CAS DataBase Reference)
    11. NIST Chemistry Reference: methyl 4-bromoquinoline-8-carboxylate(132664-48-3)
    12. EPA Substance Registry System: methyl 4-bromoquinoline-8-carboxylate(132664-48-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 132664-48-3(Hazardous Substances Data)

132664-48-3 Usage

Uses

Used in Pharmaceutical Industry:
Methyl 4-bromoquinoline-8-carboxylate is used as an intermediate in the synthesis of new drugs and bioactive molecules for its potential to contribute to the development of innovative pharmaceuticals.
Used in Medicinal Chemistry Research:
It is employed as a building block in the design and synthesis of compounds with antitumor, antiviral, and antimicrobial properties, due to its inherent biological activities and the potential for creating effective therapeutic agents.
Used in Agrochemical Production:
Methyl 4-bromoquinoline-8-carboxylate is utilized as an intermediate in the production of agrochemicals, indicating its broad applicability in different sectors beyond healthcare, contributing to agricultural advancements.

Check Digit Verification of cas no

The CAS Registry Mumber 132664-48-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,6,6 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 132664-48:
(8*1)+(7*3)+(6*2)+(5*6)+(4*6)+(3*4)+(2*4)+(1*8)=123
123 % 10 = 3
So 132664-48-3 is a valid CAS Registry Number.

132664-48-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 4-bromoquinoline-8-carboxylate

1.2 Other means of identification

Product number -
Other names 4-bromo-8-methoxycarbonylquinoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132664-48-3 SDS

132664-48-3Relevant articles and documents

RNA binding and thiolytic stability of a quinoline-containing helix-threading peptide

Krishnamurthy, Malathy,Gooch, Barry D.,Beal, Peter A.

, p. 639 - 645 (2007/10/03)

Helix-threading peptides (HTPs) bind selectively to sites predisposed to intercalation in folded RNA molecules placing peptide functional groups into the dissimilar grooves of the duplex. Here we report the design and synthesis of new HTPs with quinoline

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