1378632-40-6Relevant articles and documents
PROTEIN SECRETION INHIBITORS
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Paragraph 00354, (2022/03/09)
Provided herein are secretion inhibitors, such as inhibitors of Sec61 for example of Formula (I), methods for their preparation, related pharmaceutical compositions, and method for using the same.
Compound with multi-target inhibition effect, composition, functional molecule and application of compound
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Paragraph 0524-0527, (2021/07/17)
The invention relates to a compound with a multi-target inhibition effect, a composition, a functional molecule and application of the compound. The compound has a structure shown in a formula (I), wherein K in the formula is as shown in the specification. The compound has an inhibition effect on BET and kinase double targets and can simultaneously act on different signal channels of tumor cell growth to achieve a better treatment effect.
QUINOLINONE PYRIMIDINES COMPOSITIONS AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS
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Paragraph 0823-0825, (2016/04/19)
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where A, B, W1, W2, W3, and R1-R6 are described herein.
NEW IMIDAZOLYLKETONE DERIVATIVES
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Paragraph 0316; 0317, (2014/05/20)
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3 and R4 n are as described herein, compositions including the compounds and methods of using the compounds.
IMIDAZOLYLKETONE DERIVATIVES ASD ALDOSTERONE SYNTHASE INHIBITORS
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Page/Page column 46, (2013/08/28)
The invention provides novel compounds having the general formula (I), wherein R1, R2, R3 and R4 n are as described herein, compositions including the compounds and methods of using the compounds as inhibitors of aldosterone synthase.
