4532-96-1

Usage

Uses

Used in Organic Synthesis:
1-Isopropylimidazole is used as a building block for the synthesis of various biologically active compounds, contributing to the development of new pharmaceuticals and agrochemicals.
Used in Pharmaceutical Research:
1-Isopropylimidazole is used as a catalyst in polymerization reactions and as a reagent in the synthesis of pharmaceuticals, enabling the production of innovative and effective drugs.
Used in Specialty Chemicals:
1-Isopropylimidazole is used as an intermediate in the production of dyes and other specialty chemicals, enhancing the properties and performance of these products.
Used in Corrosion Inhibition:
1-Isopropylimidazole is used as a corrosion inhibitor in the production of corrosion inhibitors, surfactants, and lubricants, providing protection against corrosion in various industrial applications.
Used in Electroplating and Metal Finishing:
1-Isopropylimidazole is used in electroplating and metal finishing processes, improving the quality and durability of metal surfaces.
Used in Cooling Water Systems:
1-Isopropylimidazole is used as a corrosion inhibitor in cooling water systems, preventing corrosion and extending the life of equipment and infrastructure.

Upstream product

• 50-00-0 formaldehyd 
• 131543-46-9 Glyoxal 
• 75-31-0 isopropylamine 
• 288-32-4 1H-imidazole 
• 75-30-9 2-iodo-propane 
• 75-26-3 isopropyl bromide 

Downstream Products

• 873203-76-0 [1-OH-4,6-di-tert-butyl-2-CH₂C₃H₃N₂(isopropyl)-C₆H₂]Cl 
• 121346-84-7 1-isopropyl-2-(4-methoxybenzenesulphonyl)-imidazole 
• 938051-33-3 1-benzyl-3-isopropylimidazolium bromide 
• 1202570-70-4 1-(i-propyl)-3-N-(benzylacetamido)imidazolium chloride 
• 1207863-91-9 1-isopropyl-3-[(2-methoxyphenyl)aminocarbonylmethyl]imidazolium chloride 
• 53332-64-2 N-isopropyl-1H-imidazole-2-carboxaldehyde 
• 84606-45-1 1-isopropyl-2-methyl imidazole 

Relevant academic research and scientific papers

Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications

A novel approach towards the synthesis of radiolabeled organometallic rhenium complexes is presented. We successfully synthesized and analyzed the first 188Re-labeled N-heterocyclic biscarbene complex, trans-dioxobis(1,1′-methylene-bis(3,3′-diisopropylimidazolium-2- ylidene))188rhenium(V) hexafluorophosphate (188Re-4) via transmetalation using an air-stable and moisture-stable silver(I) biscarbene complex. In order to assess the viability of this complex as a potential lead structure for in vivo applications, the stability of the 188Re-NHC complex was tested in physiologically relevant media. Ultimately, our studies illustrate that the complex we synthesized dissociates rapidly and is therefore unsuitable for use in radiopharmaceuticals. However, it is clear that the transmetalation approach we have developed is a rapid, robust, and mild method for the synthesis of new 188Re-labeled carbene complexes. Copyright

Synthesis, structures, and reactivity of chelating bis-N-heterocyclic- carbene complexes of iron(II)

Distorted tetrahedral (bis-carbene)FeX2 complexes can be synthesized by direct metalation of chelating bisimidazolium salts, containing CH2 or phenylene linkers, with Fe(N(SiMe3) 2)2(THF). For methylenebis(N-R-imidazole-2-ylidene) ((RC)2CH2), the high-spin complexes (( RC)2CH2)FeX2 (R = iPr or 2,6-di-isopropylphenyl (DIPP), X = I or Br) are isolated in good to excellent yield. In contrast the phenylene-linked congener ((iPrC) 2Ph)FeI2 cannot be separated from two co-products, one of which was characterized by X-ray crystallography and zero-field 57Fe Moessbauer spectroscopy as the square-planar complex [((iPrC) 2Ph)2Fe[I2. The disparate reactivity toward Fe(N(SiMe3)2)2(THF) is due to the increase in linker length and decrease in linker flexibility of the phenylene-linked bis-carbene ligand relative to the methylene analogue. The short, flexible -CH2- linker projects the azole rings into the xy plane (defined as the carbene-Fe bond directions) and away from the pseudoaxial anionic substituent, whereas the inflexible phenylene linker ((RC) 2Ph) orientates both azole rings into the z direction, which in ((RC)2Y)FeX2 species (Y = CH2 or phenylene) has the greatest steric crowding. Metallacycle distortion in tetrahedral ((RC)2Ph)FeX2 is necessary to project the azoles into the xy plane, destabilizing this geometry. Addition of CO to ((DIPPC)2CH2)FeI2 forms cis-((DIPPC)2CH2)FeI2(CO) 2, in which the carbene ligands are strong σ donors based on ν(CO). Halide metathesis of ((DIPPC)2CH 2)FeI2 with NaSMe cleanly forms ((DIPPC) 2CH2)FeI(SMe), while attempts to exchange the second iodide for -SMe led to carbene dissociation.

Synthesis, crystal structures and blue emission of zinc(II) halide complexes of 1-alkyl-imidazole and (-)-nicotine

Zn(II) halide complexes of the form L2ZnX2 (X =Cl, Br, I) containing bio-relevant or bio-related ligands like 1-alkyl-imidazoles (alkyl=methyl, ethyl and iso-propyl) or (-)-nicotine are presented. All complexes were characterized by 1H NMR spectroscopy, mass spectrometry and elemental analysis. The molecular structures of the majority of complexes were determined by single crystal X-ray diffraction. The zinc ion exists in a tetrahedral environment coordinated by two halide anions and two nitrogen atoms of the N-heterocycles. Upon photoexcitation the nicotine complexes feature a blue emission which we tentatively assign to phosphorescence.

A planar anthracene–imidazolium/anthracene–benzimidazolium cation system in a spherical polyoxometalate matrix: Synthesis, crystallography and spectroscopy

A series of ion–pair compounds, comprising of Lindqvist type isopolyanions viz., [Mo6O19]2?and [W6O19]2?as the counter anions and anthracene–imidazolium/anthracene–benzimidazolium as counter cations, have been described. Structures of the isolated stoichiometric solids have been unambiguously determined by single crystal X-ray diffraction analysis. In spite of the structural incompatibility between anthracene (planar) and the present polyoxometalate anions (spherical), coulombic and several intermolecular weak interactions, e.g. C–H?O, C–H?π, π–π, etc. compensate the destabilization energy raised due to presence of the structurally mis-matched components in the respective crystal lattices. Single-crystal- as well as powder X-ray-diffraction (PXRD) analyses reveal iso-structural relationship between the hexamolybdates- and hexatungstates-associated ion pair compounds. Conformational variation has been observed in the crystal structures containing benzyl benzimidazolium counter cations. Diffuse reflectance electronic absorption spectral studies are performed to understand the relatively intense color of the title compounds in their solid states in comparison to their respective solution states.

Process for the preparation of 1-hexene and 1-oxtene

The present invention relates to a manufacturing method of 1-hexene and 1-octene from an olefin under the presence of a catalyst composition. The catalyst composition comprises: at least one type of an organic ligand compound selected from the group consisting of a compound represented by chemical formula 1, a compound represented by chemical formula 2, and a compound represented by chemical formula 3; at least one type of transition metal or a transition metal precursor selected from the group consisting of group IV to group XII elements; and a promotor. The manufacturing method of the present invention reduces generation of byproducts, and can manufacture 1-hexene and 1-octene from an olefin with high selectivity and reaction activity.

N-heterocyclic carbene-catalyzed α-alkylation of ketones with primary alcohols

Several N-heterocyclic carbene precursors are synthesized and used in the α-alkylations of ketones with primary alcohols. With the assistance of a base, these N-heterocyclic carbenes can catalyze the reaction smoothly to furnish dialkylated ketones in good-to-excellent yields.

Convenient syntheses of bulky group containing imidazolium ionic liquids

We report syntheses of bulky group containing imidazolium based ionic liquids. The bulky groups were introduced at N-1, C-2, and N-3 positions of the imidazole ring using convenient methodologies. Copyright

USE OF PT-AND PD-BIS-AND TETRA-CARBON COMPLEXES WITH BRIDGED CARBON LIGANDS IN OLEDS

The use of Pt- and Pd-bis- and tetracarbene complexes with bridged carbene ligands in organic light-emitting diodes, organic light-emitting diodes comprising at least one aforementioned Pt- or Pd-carbene complex, at least one transition metal-carbene comp

Synthesis of 1,3-dialkylimidazolium and 1,3-dialkylbenzimidazolium salts

A number of N-alkylimidazoles and N-alkylbenzimidazoles were synthesized by reactions of imidazole and benzimidazole with alkyl halides. The reaction rate increases by a factor of 2 to 3 under conditions of microwave activation. Subsequent treatment of the resulting N-alkylazoles with alkyl halides afforded the corresponding 1,3-dialkylimidazolium and 1,3-dialkylbenzimidazolium halides.

Optically active iridium imidazol-2-ylidene-oxazoline complexes: Preparation and use in asymmetric hydrogenation of arylalkenes

This work explores the potential of iridium complexes of the N-heterocyclic carbene oxazoline ligands 1 in asymmetric hydrogenations of arylalkenes. The accessible carbene precursors, imidazolium salts 2, and robust iridium complexes 5 facilitated a disco