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5-METHYL-4-(4-METHYLPHENYL)-1,3-THIAZOL-2-AMINE, commonly referred to as MTMT, is a chemical compound characterized by its thiazole ring structure. It is a derivative of thiazole, featuring a methyl and a 4-methylphenyl group attached to it. 5-METHYL-4-(4-METHYLPHENYL)-1,3-THIAZOL-2-AMINE has garnered interest due to its potential pharmacological and biological activities, particularly as an antifungal agent. Its applications extend to the realms of medicinal chemistry and drug development, with ongoing research aimed at uncovering its full spectrum of properties and uses.

16942-66-8

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16942-66-8 Usage

Uses

Used in Pharmaceutical Industry:
5-METHYL-4-(4-METHYLPHENYL)-1,3-THIAZOL-2-AMINE is used as a potential antifungal agent for its ability to combat fungal infections. Its unique chemical structure allows it to target and inhibit the growth of various fungi, making it a valuable asset in the development of new antifungal medications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-METHYL-4-(4-METHYLPHENYL)-1,3-THIAZOL-2-AMINE serves as a promising candidate for the development of novel therapeutic agents. Its chemical properties and potential biological activities make it a versatile building block for the synthesis of new drugs with diverse applications.
Used in Drug Development:
5-METHYL-4-(4-METHYLPHENYL)-1,3-THIAZOL-2-AMINE is utilized in drug development to explore its potential as a lead compound for creating new pharmaceuticals. Its unique structure and biological activities provide a foundation for further optimization and modification to enhance its therapeutic efficacy and safety profile.

Check Digit Verification of cas no

The CAS Registry Mumber 16942-66-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,4 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 16942-66:
(7*1)+(6*6)+(5*9)+(4*4)+(3*2)+(2*6)+(1*6)=128
128 % 10 = 8
So 16942-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2S/c1-7-3-5-9(6-4-7)10-8(2)14-11(12)13-10/h3-6H,1-2H3,(H2,12,13)

16942-66-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Methyl-4-(4-methylphenyl)-1,3-thiazol-2-amine

1.2 Other means of identification

Product number -
Other names 5-methyl-4-p-tolyl-thiazol-2-ylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16942-66-8 SDS

16942-66-8Relevant articles and documents

Promiscuous 2-aminothiazoles (PrATs): A frequent hitting scaffold

Devine, Shane M.,Mulcair, Mark D.,Debono, Cael O.,Leung, Eleanor W. W.,Nissink, J. Willem M.,Lim, San Sui,Chandrashekaran, Indu R.,Vazirani, Mansha,Mohanty, Biswaranjan,Simpson, Jamie S.,Baell, Jonathan B.,Scammells, Peter J.,Norton, Raymond S.,Scanlon, Martin J.

, p. 1205 - 1214 (2015)

We have identified a class of molecules, known as 2-aminothiazoles (2-ATs), as frequent-hitting fragments in biophysical binding assays. This was exemplified by 4-phenylthiazol-2-amine being identified as a hit in 14/14 screens against a diverse range of

Synthesis and antimicrobial activities of some novel 2,3-substituted-1,3-thiazolidin-4-ones derived from 2-amino-1,3-thiazole

Maher

, p. 2794 - 2798 (2017/11/10)

New 2,3-substituted-1,3-thiazolidin-4-one (6a-f) were prepared by cyclocondensation of 2-[6-(4-chlorobenzyloxy)-2-naphthyliden]-4-(4-substituted phenyl)-5-methyl-1,3-thiazole (5a-f) and mercaptoacetic acid in benzene. The synthesized compounds were charac

IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR

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Paragraph 00266, (2013/06/27)

Compounds, compositions, and methods for modulation of Hec1/Nek2 interaction are provided. Such compounds disrupt Nek2/Hec1 binding and may be useful as chemotherapeutic agents for neoplastic diseases

Modulators Of HEC1 Activity And Methods Therefor

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Page/Page column 9-10, (2011/10/10)

Compounds, compositions, and methods for modulation of Hec1/Nek2 interaction are provided. Especially preferred compounds disrupt Nek2/Hec1 binding and are therefore useful as chemotherapeutic agent for neoplastic diseases.

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