2375201-60-6 Usage
Uses
Used in Bioconjugation and Biomolecular Labeling:
N-(3-(5-aminonaphthalen-1-yl)propyl)biotinamide is used as a bioconjugation agent for the attachment of biomolecules to other molecules or surfaces. Its ability to bind with high specificity and affinity makes it an ideal candidate for the development of biosensors and other diagnostic tools.
Used in Studying and Visualizing Protein-Protein Interactions:
N-(3-(5-aminonaphthalen-1-yl)propyl)biotinamide is used as a labeling agent for visualizing and studying protein-protein interactions. Its fluorescent properties allow researchers to track and monitor the behavior of proteins within biological systems, providing valuable insights into their functions and interactions.
Used in Diagnostic Assays and Imaging Techniques:
N-(3-(5-aminonaphthalen-1-yl)propyl)biotinamide is used as a component in the development of diagnostic assays and imaging techniques for biomedical research and clinical diagnostics. Its versatility and compatibility with various detection methods make it a valuable tool for the identification and tracking of specific biomolecules.
Used in Biomedical Research and Clinical Diagnostics:
N-(3-(5-aminonaphthalen-1-yl)propyl)biotinamide is used as a research tool in the field of biomedical research and clinical diagnostics. Its unique properties and applications contribute to the advancement of our understanding of biological processes and the development of new diagnostic and therapeutic approaches.
Check Digit Verification of cas no
The CAS Registry Mumber 2375201-60-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,3,7,5,2,0 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2375201-60:
(9*2)+(8*3)+(7*7)+(6*5)+(5*2)+(4*0)+(3*1)+(2*6)+(1*0)=146
146 % 10 = 6
So 2375201-60-6 is a valid CAS Registry Number.
2375201-60-6Relevant articles and documents
Expanding APEX2 Substrates for Proximity-Dependent Labeling of Nucleic Acids and Proteins in Living Cells
Zhou, Ying,Wang, Gang,Wang, Pengchong,Li, Zeyao,Yue, Tieqiang,Wang, Jianbin,Zou, Peng
, p. 11763 - 11767 (2019/08/08)
The subcellular organization of biomolecules such as proteins and nucleic acids is intimately linked to their biological functions. APEX2, an engineered ascorbate peroxidase that enables proximity-dependent labeling of proteins in living cells, has emerged as a powerful tool for deciphering the molecular architecture of various subcellular structures. However, only phenolic compounds have thus far been employed as APEX2 substrates, and the resulting phenoxyl radicals preferentially react with electron-rich amino acid residues. This narrow scope of substrates could potentially limit the application of APEX2. In this study, we screened a panel of aromatic compounds and identified biotin-conjugated arylamines as novel probes with significantly higher reactivity towards nucleic acids. As a demonstration of the spatial specificity and depth of coverage in mammalian cells, we applied APEX2 labeling with biotin-aniline (Btn-An) in the mitochondrial matrix, capturing all 13 mitochondrial messenger RNAs and none of the cytoplasmic RNAs. APEX2-mediated Btn-An labeling of RNA is thus a promising method for mapping the subcellular transcriptome, which could shed light on its functions in cell physiology.
