417724-81-3 Usage
Uses
Used in Pharmaceutical Industry:
7-methoxy-4-oxo-1,4-dihydroquinoline-6-carboxamide is used as a metabolite for Lenvatinib, an orally active inhibitor of multiple receptor tyrosine kinases such as VEGF, FGF, and SCF receptors. Its presence in the body indicates the bioavailability and metabolic activity of Lenvatinib, which is crucial for understanding the drug's efficacy and safety profile in treating various diseases, particularly cancer.
Used in Cancer Treatment:
As a metabolite of Lenvatinib, 7-methoxy-4-oxo-1,4-dihydroquinoline-6-carboxamide contributes to the overall therapeutic effect of Lenvatinib in cancer treatment. Lenvatinib's inhibition of multiple receptor tyrosine kinases, including VEGF, FGF, and SCF receptors, helps in suppressing tumor growth and angiogenesis, making it a valuable compound in the fight against cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 417724-81-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,1,7,7,2 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 417724-81:
(8*4)+(7*1)+(6*7)+(5*7)+(4*2)+(3*4)+(2*8)+(1*1)=153
153 % 10 = 3
So 417724-81-3 is a valid CAS Registry Number.
417724-81-3Relevant articles and documents
Synthesis method of lenvatinib derivative key intermediate
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Paragraph 0012; 0026-0028, (2021/01/20)
The invention provides a synthesis method of lenvatinib derivative key intermediate 7-methoxy-4-oxo-1, 4-dihydroquinoline-6-carbonitrile, and the synthesis method has the advantages of simple synthesis steps, short reaction time, mild reaction conditions, easiness in purification, high yield and low cost, and a good industrial production prospect.
