944901-07-9 Usage
Uses
Used in Pharmaceutical Industry:
2-Bromo-4-methoxy-1-(trifluoromethyl)benzene is used as a reactant in the synthetic preparation of amino(aryloxy)propanol derivatives. These derivatives serve as coactivator-associated arginine methyltransferase (CARM1) inhibitors, which are important in the development of drugs targeting various diseases and conditions. 2-Bromo-4-methoxy-1-(trifluoromethyl)benzene's unique structure allows for the creation of specific inhibitors that can modulate the activity of CARM1, a key enzyme involved in various biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 944901-07-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,0 and 1 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 944901-07:
(8*9)+(7*4)+(6*4)+(5*9)+(4*0)+(3*1)+(2*0)+(1*7)=179
179 % 10 = 9
So 944901-07-9 is a valid CAS Registry Number.
944901-07-9Relevant articles and documents
CARM1 INHIBITORS AND USES THEREOF
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Paragraph 00433, (2016/04/09)
Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARMl activity. Methods of using the compounds for treating CARMl -mediated disorders are also described.
