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956139-21-2

(6-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate is an oligonucleotide analog that features cationic intersubunit linkages. This unique structure allows it to be utilized in various applications, particularly in the realm of genetic research and medicine.

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  • N,N-Dimethylphosphoramidochloridic acid [(2S,6R)-6-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester

    Cas No: 956139-21-2

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  • 10 Milligram

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  • Morpholino C subunit; 5-Trityl-N-Benzoyl-Morpholino Cytidine; (6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate

    Cas No: 956139-21-2

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  • (6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate

    Cas No: 956139-21-2

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  • Cas no.956139-21-2 98% (6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate

    Cas No: 956139-21-2

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  • Win-Win chemical Co.Ltd
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  • 956139-21-2 Structure

  • Basic information

    1. Product Name: (6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
    2. Synonyms: (6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate;5-Trityl-N-Benzoyl-Morpholino Cytidine;Morpholino C subunit;N,N-Dimethylphosphoramidochloridic acid [(2S,6R)-6-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester;[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
    3. CAS NO:956139-21-2
    4. Molecular Formula: C37H37ClN5O5P
    5. Molecular Weight: 698.146941
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 956139-21-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.30±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 8.63±0.20(Predicted)
    10. CAS DataBase Reference: (6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate(CAS DataBase Reference)
    11. NIST Chemistry Reference: (6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate(956139-21-2)
    12. EPA Substance Registry System: (6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate(956139-21-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 956139-21-2(Hazardous Substances Data)

956139-21-2 Usage

Uses

Used in Antisense Modulation of Gene Expression:
(6-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate is used as an antisense modulator for the regulation of gene expression. Its cationic intersubunit linkages enable it to bind to specific nucleic acid sequences, modulating the expression of target genes and offering potential therapeutic benefits in treating genetic disorders and diseases.
Used in Antibacterial Applications:
In the field of microbiology, (6-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate has shown potential as an antibacterial agent. Its ability to interact with nucleic acids can disrupt bacterial function, offering a novel approach to combat antibiotic-resistant bacteria and contributing to the development of new antimicrobial therapies.
Used in Pharmaceutical Industry:
(6-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate is used as a key component in the development of new pharmaceuticals. Its unique properties make it a valuable asset in the creation of drugs targeting specific genetic pathways, potentially leading to more effective treatments for a variety of conditions.
Used in Research and Development:
In the scientific community, (6-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate serves as an important tool in research and development. Its application in studying gene expression and nucleic acid interactions can lead to a better understanding of genetic mechanisms and the discovery of new therapeutic targets.

Check Digit Verification of cas no

The CAS Registry Mumber 956139-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,6,1,3 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 956139-21:
(8*9)+(7*5)+(6*6)+(5*1)+(4*3)+(3*9)+(2*2)+(1*1)=192
192 % 10 = 2
So 956139-21-2 is a valid CAS Registry Number.

956139-21-2Downstream Products

956139-21-2Relevant articles and documents

Lithium bromide-DBU mediated synthesis of chlorophosphoramidate-activated morpholino nucleoside subunits

Pattanayak, Sankha,Sinha, Surajit

, p. 6714 - 6717 (2013/01/15)

An efficient and rapid protocol for the synthesis of chlorophosphoramidate- activated morpholino subunits has been developed. A unique combination of lithium bromide-DBU has been found to activate the 7′-hydroxyl toward the reaction. All the four morpholi

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