97654-99-4Relevant articles and documents
A novel azobenzene-based fluorescent sensor for selective detection of mercury ion
Gao, Yan,Song, Jian,Wang, Wei
, p. 749 - 751 (2011)
A highly sensitive fluorescent probe (3) for selective detection of mercury based on an azobenzene derivative with 1,3,4-triazole units has been designed, synthesized, and examined for their cation recognition abilities toward various cations by UV-vis, f
Photoswitchable Conjugated Oligoelectrolytes for a Light-Induced Change of Membrane Morphology
Bazan, Guillermo C.,Leifert, Dirk,Limwongyut, Jakkarin,Mikhailovsky, Alexander A.,Moreland, Alex S.
, p. 20333 - 20337 (2020/09/07)
The synthesis of a new conjugated oligoelectrolyte (COE), namely DSAzB, is described, which contains a conjugated core bearing a diazene moiety in the center of its electronically delocalized structure. Similar to structurally related phenylenevinylene-based COEs, DSAzB readily intercalates into model and natural lipid bilayer membranes. Photoinduced isomerization transforms the linear trans COE into a bent or C-shape form. It is thereby possible to introduce DSAzB into the bilayer of a cell and disrupt its integrity by irradiation with light. This leads to controlled permeabilization of membranes, as demonstrated by the release of calcein from DMPG/DMPC vesicles and by propidium iodide influx experiments on S. epidermidis. Both experiments support that the permeabilization is selective for the light stimulus, highly efficient, and repeatable. Target-selective and photoinduced actions demonstrated by DSAzB may have broad applications in biocatalysis and related biotechnologies.
Optical Control of Cardiac Function with a Photoswitchable Muscarinic Agonist
Riefolo, Fabio,Matera, Carlo,Garrido-Charles, Aida,Gomila, Alexandre M. J.,Sortino, Rosalba,Agnetta, Luca,Claro, Enrique,Masgrau, Roser,Holzgrabe, Ulrike,Batlle, Montserrat,Decker, Michael,Guasch, Eduard,Gorostiza, Pau
, p. 7628 - 7636 (2019/05/16)
Light-triggered reversible modulation of physiological functions offers the promise of enabling on-demand spatiotemporally controlled therapeutic interventions. Optogenetics has been successfully implemented in the heart, but significant barriers to its u
Azobenzene-Bridged Expanded "Texas-sized" Box: A Dual-Responsive Receptor for Aryl Dianion Encapsulation
Chi, Xiaodong,Cen, Wanglai,Queenan, Jack A.,Long, Lingliang,Lynch, Vincent M.,Khashab, Niveen M.,Sessler, Jonathan L.
, p. 6468 - 6472 (2019/05/06)
We report an expanded "Texas-sized" molecular box (AzoTxSB) that incorporates photoresponsive azobenzene bridging subunits and anion recognition motifs. The shape of this box can be switched through light induced E ? Z photoisomerization of the constituen
Dimeric surfactant containing azobenzene group, and application thereof
-
, (2019/07/04)
The invention discloses a dimeric surfactant containing an azobenzene group, and an application thereof, and belongs to the fields of surfactant science and application technologies thereof. Sodium oleate and a dimeric quaternary ammonium salt are compoun
Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties
Agnetta, Luca,Bermudez, Marcel,Riefolo, Fabio,Matera, Carlo,Claro, Enrique,Messerer, Regina,Littmann, Timo,Wolber, Gerhard,Holzgrabe, Ulrike,Decker, Michael
, p. 3009 - 3020 (2019/05/08)
Red-shifted azobenzene scaffolds have emerged as useful molecular photoswitches to expand potential applications of photopharmacological tool compounds. As one of them, tetra-ortho-fluoro azobenzene is well compatible for the design of visible-light-responsive systems, providing stable and bidirectional photoconversions and tissue-compatible characteristics. Using the unsubstituted azobenzene core and its tetra-ortho-fluorinated analogue, we have developed a set of uni- and bivalent photoswitchable toolbox derivatives of the highly potent muscarinic acetylcholine receptor agonist iperoxo. We investigated the impact of the substitution pattern on receptor activity and evaluated the different binding modes. Compounds 9b and 15b show excellent photochemical properties and biological activity as fluorination of the azobenzene core alters not only the photochromic behavior but also the pharmacological profile at the muscarinic M1 receptor. These findings demonstrate that incorporation of fluorinated azobenzenes not just may alter photophysical properties but can exhibit a considerably different biological profile that has to be carefully investigated.
Comparison of computationally cheap methods for providing insight into the crystal packing of highly bromomethylated azobenzenes
Vande Velde, Christophe M. L.,Zeller, Matthias,Azov, Vladimir A.
, p. 1692 - 1702 (2018/11/30)
For five bromomethylated azobenzenes, namely (E)-[4-(bromomethyl)phenyl][4-(dibromomethyl)phenyl]diazene, C14H11Br3N2, (E)-1,2-bis[4-(dibromomethyl)phenyl]diazene, C14H10Br4Nsub
A photo-responsive poly(amide-triazole) physical organogel bearing azobenzene residues in the main chain
Wang, Huai-Zhen,Chow, Hak-Fun
, p. 8391 - 8394 (2018/08/01)
The synthesis of a click poly(amide-triazole) bearing multiple azobenzene units along the main chain was reported. The polymer was found to form strong physical polymer organogels. This structural design facilitates a much more efficient photomechanical e
Insights into the Difference Between Rotaxane and Pseudorotaxane
Sun, He-Lue,Zhang, Heng-Yi,Dai, Zhen,Han, Xu,Liu, Yu
supporting information, p. 265 - 270 (2017/02/05)
Rotaxane and pseudorotaxane are two types of mechanically interlocked molecular architectures, and there is a clear topological difference and boundary between them. In this work, a “suggested [2]rotaxane 1?α-CD” was constructed based on axle molecule 1 b
Switching Process Consisting of Three Isomeric States of an Azobenzene Unit
Adam, Abdulselam,Haberhauer, Gebhard
, p. 9708 - 9713 (2017/07/24)
Azobenzene and its derivatives are among the most commonly used switching units in organic chemistry. The switching process consists of two states, in which the trans isomer has a stretched and the cis isomer a compact form. Here, we have designed a syste
