2-Methyl butyric acid (116-53-0) 's Synthetic route

Effect of particle restructuring during reduction processes over polydopamine-supported Pd nanoparticles

Gazdag, Tamás  Baróthi, ádám  Juhász, Koppány Levente  Kunfi, Attila  Németh, Péter  Sápi, András  Kukovecz, ákos  Kónya, Zoltán  Szori, Kornél  London, Gábor

The effect of catalyst restructuring on the polydopamine-supported Pd catalyzed transfer hydrogenation of ethyl 4-nitrobenzoate and the catalytic hydrogenation of (E)-2-methyl-2-butenoic acid is reported. Transmission electron microscopy investigation of different catalyst pre-treatment and reaction conditions revealed high catalytic activity in both reactions unless drastic aggregation of the active metal occurred. In the transfer hydrogenation reaction aggregation was primarily dependent on the H-source used, while in the catalytic hydrogenation additives in combination with the reductive environment led to extensive Pd aggregation and thus decreased catalytic activity. The enantioselective hydrogenation of (E)-2-methyl-2-butenoic acid showed increased enantioselectivity and decreased conversion with increased particle size.