Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

Name	2-((4-Chlorophenyl)acetyl)benzoic acid	EINECS	258-444-8
CAS No.	53242-76-5	Density	1.332 g/cm³
PSA	54.37000	LogP	3.46360
Solubility	N/A	Melting Point	N/A
Formula	C₁₅H₁₁ClO₃	Boiling Point	456.8 °C at 760 mmHg
Molecular Weight	274.704	Flash Point	230.1 °C
Transport Information	N/A	Appearance	off-white crystalline powder
Safety		Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	Benzoicacid, 2-[(4-chlorophenyl)acetyl]- (9CI);	Article Data	3

2-((4-Chlorophenyl)acetyl)benzoic acid Synthetic route

: 1878-66-6
4-chlorophenylacetic Acid

: 85-44-9
phthalic anhydride

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

Conditions

Conditions	Yield
Stage #1: 4-chlorophenylacetic Acid; phthalic anhydride With sodium acetate at 240 - 250℃; for 3h; Stage #2: With water; sodium hydroxide In water for 4h; Time; Reflux;	80%

: 105279-16-1
(Z)-3-(4-chlorophenyl)methylidenephthalide

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

Conditions

Conditions	Yield
With sodium hydroxide for 2h; Heating; Yield given;

: 1878-66-6
4-chlorophenylacetic Acid

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: CH3COONa / 3 h / 245 - 250 °C 2: aq. NaOH / 2 h / Heating View Scheme

: 85-44-9
phthalic anhydride

3-<2-carboxy-phenyl>-pyridine-carboxylic acid-(2): 3-<2-carboxy-phenyl>-pyridine-carboxylic acid-(2)

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: CH3COONa / 3 h / 245 - 250 °C 2: aq. NaOH / 2 h / Heating View Scheme

: 20526-97-0
3-(4-chlorobenzylidene)-2-benzofuran-1(3H)-one

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

: 105279-16-1
(Z)-3-(4-chlorophenyl)methylidenephthalide

Conditions

Conditions	Yield
With O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 12h; Inert atmosphere;	91%

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

: 53242-88-9
4-[(4-chlorophenyl)methyl]-1(2H)-phthalazinone

Conditions

Conditions	Yield
With sodium hydroxide; hydrazinium sulfate for 2h; Heating;	90%

: 186581-53-3, 908094-01-9
diazomethane

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

: 61653-04-1
methyl 2-(4-chlorophenylacetyl)benzoate

Conditions

Conditions	Yield
In diethyl ether

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

: 2-Benzoyl-1-(hexahydro-1-methyl-1H-azepin-4-yl)hydrazin-hydrochlorid

: 58581-89-8
azelastine

Conditions

Conditions	Yield
With hydrogenchloride; potassium hydroxide 1.) reflux, 3 h, 2.) methanol, reflux, 2 h; Yield given. Multistep reaction;

: 53242-76-5
2‐(4-chlorophenylacetyl)benzoic acid

: 4-(p-Chlorbenzyl)-2-<2-(N-methylpyrrolidin-2-yl)-ethyl>-1(2H)-phthalazinon

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 90 percent / hydrazine sulfate, aq. NaOH / 2 h / Heating 2: aq. NaOH / 1 h / 70 °C View Scheme

2-((4-Chlorophenyl)acetyl)benzoic acid Chemical Properties

IUPAC name: 2-[2-(4-Chlorophenyl)acetyl]benzoic acid
Molecular Formula: C₁₅H₁₁ClO₃
Molecular Weight: 274.70 g/mol
EINECS: 258-444-8
Index of Refraction: 1.621
Surface Tension: 55.4 dyne/cm
Density: 1.332 g/cm³
Flash Point: 230.1 °C
Enthalpy of Vaporization: 75.54 kJ/mol
Boiling Point: 456.8 °C at 760 mmHg
Vapour Pressure: 3.87E-09 mmHg at 25 °C
Product Category of 2-((4-Chlorophenyl)acetyl)benzoic acid (CAS NO.53242-76-5): Organic acids;(intermediate of azelastine hcl)
Following is the structure of 2-((4-Chlorophenyl)acetyl)benzoic acid (CAS NO.53242-76-5):

Canonical SMILES: C1=CC=C(C(=C1)C(=O)CC2=CC=C(C=C2)Cl)C(=O)O
InChI: InChI=1S/C15H11ClO3/c16-11-7-5-10(6-8-11)9-14(17)12-3-1-2-4-13(12)15(18)19/h1-8H,9H2,(H,18,19)
InChIKey: BDSINYHJZLINDJ-UHFFFAOYSA-N

2-((4-Chlorophenyl)acetyl)benzoic acid Specification

2-((4-Chlorophenyl)acetyl)benzoic acid , its cas register number is 53242-76-5. It also can be called 2-[2-(4-Chlorophenyl)acetyl]benzoic acid .

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 53242-76-5