Basic Information | Post buying leads | Suppliers | Cas Database |
Conditions | Yield |
---|---|
With pyrographite; hydrazine hydrate In ethanol for 1.16667h; Time; Reflux; | 100% |
With hydrazine hydrate In ethanol for 3.5h; Reflux; | 91% |
With ammonium hydroxide; hydrazine hydrate |
Conditions | Yield |
---|---|
With bismuth (III) nitrate pentahydrate; palladium diacetate In 2,2,2-trifluoroethanol; trifluoroacetic acid at 20 - 90℃; for 24h; Inert atmosphere; | 69% |
2,4-dinitro-1-ethoxybenzene
A
2-Amino-4-nitroethoxybenzen
B
(2,4-dinitro-phenyl)-hydrazine
Conditions | Yield |
---|---|
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h; | A 6% B n/a |
2-(2,4-dinitrophenoxy)ethanol
A
2-(2-amino-4-nitro-phenoxy)-ethanol
B
(2,4-dinitro-phenyl)-hydrazine
Conditions | Yield |
---|---|
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h; | A 1% B n/a |
2,4-dinitrophenyl isopropyl ether
A
2-isopropoxy-5-nitro-aniline
B
(2,4-dinitro-phenyl)-hydrazine
Conditions | Yield |
---|---|
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h; | A 1% B n/a |
2,4-dinitrophenyl 2-methoxyethyl ether
A
2-(2-methoxy-ethoxy)-5-nitro-aniline
B
(2,4-dinitro-phenyl)-hydrazine
Conditions | Yield |
---|---|
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h; | A 1% B n/a |
3-(2,4-dinitro-phenoxy)-propane-1,2-diol
A
3-(2-amino-4-nitro-phenoxy)-propane-1,2-diol
B
(2,4-dinitro-phenyl)-hydrazine
Conditions | Yield |
---|---|
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 3h; | A 1% B n/a |
2,4-dinitrophenyl phenyl ether
A
5-nitro-2-phenoxy-aniline
B
(2,4-dinitro-phenyl)-hydrazine
Conditions | Yield |
---|---|
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 3h; | A 0.5% B n/a |
Conditions | Yield |
---|---|
With ethanol; hydrazine hydrate |
Conditions | Yield |
---|---|
With ethanol; hydrazine hydrate | |
With ethanol; hydrazine hydrate; acetic acid |
The 2,4-Dinitrophenylhydrazine, with the CAS registry number 119-26-6, is also known as 1-Hydrazino-2,4-dinitrobenzene.It belongs to the product Chemical Reagent.Its EINECS number is 204-309-3. This chemical's molecular formula is C6H6N4O4 and molecular weight is 198.13. What's more,Its systematic name is (2,4-Dinitrophenyl)hydrazine.And it is Used for determination of serum transaminase valley - and c - grass substrate supporting reagents.
Physical properties about 2,4-Dinitrophenylhydrazine are:(1)ACD/LogP: 1.454; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.45; (4)ACD/LogD (pH 7.4): 1.45; (5)ACD/BCF (pH 5.5): 7.50; (6)ACD/BCF (pH 7.4): 7.50; (7)ACD/KOC (pH 5.5): 147.21; (8)ACD/KOC (pH 7.4): 147.29; (9)#Freely Rotating Bonds: 4 ; (10)Index of Refraction: 1.731; (11)Molar Refractivity: 47.856 cm3; (12)Molar Volume: 119.744 cm3; (13)Surface Tension: 87.6439971923828 dyne/cm; (14)Density: 1.655 g/cm3; (15)Flash Point: 182.773 °C; (16)Enthalpy of Vaporization: 62.652 kJ/mol; (17)Boiling Point: 378.603 °C at 760 mmHg; (18)Vapour Pressure: 0 mmHg at 25°C.
Preparation: 2,4-Dinitrophenylhydrazine can be prepared by hydrazine sulfate and 2,4-dinitrochlorobenzene.
The 2,4-Dinitrophenylhydrazine is Highly Flammable,Harmful. When you are using it, please be cautious about it as the following: (1)Explosive when dry; (2)Highly Flammable; (3)Harmful if swallowed; (4)Limited evidence of a carcinogenic effect; (5)This material and its container must be disposed of in a safe way; (6)In case of accident or if you feel unwell, seek medical advice immediately (show label where possible); (7)Wear suitable protective clothing; (8)Wear suitable gloves; (9)Keep away from sources of ignition-No smoking.
You can still convert the following datas into molecular structure:
(1)SMILES:c1cc(c(cc1[N+](=O)[O-])[N+](=O)[O-])NN;
(2)Std. InChI:InChI=1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2;
(3)Std. InChIKey:HORQAOAYAYGIBM-UHFFFAOYSA-N.
The toxicity data of 2,4-Dinitrophenylhydrazine as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 450mg/kg (450mg/kg) | Cancer Research. Vol. 41, Pg. 1469, 1981. | |
rat | LD | oral | > 500mg/kg (500mg/kg) | National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 25, 1953. |