Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

Name	3-Methyl-2-butanone	EINECS	209-264-3
CAS No.	563-80-4	Density	0.793 g/cm³
PSA	17.07000	LogP	1.23140
Solubility	6 g/L (20 ºC)	Melting Point	-92 °C(lit.)
Formula	C₅H₁₀O	Boiling Point	78.3 °C at 760 mmHg
Molecular Weight	86.1338	Flash Point	6 °C
Transport Information	UN 2397 3/PG 2	Appearance	clear colourless liquid
Safety	9-16-33	Risk Codes	11
Molecular Structure		Hazard Symbols	F
Synonyms	2-Acetylpropane;2-Methylbutan-3-one;Isopropyl methyl ketone;MIPK;Methylisopropyl ketone;	Article Data	328

3-Methyl-2-butanone Synthetic route

: 630-19-3
pivalaldehyde

: 563-80-4
3-methyl-butan-2-one

Conditions

Conditions	Yield
With fluoroboric acid Rearrangement;	100%
With gallium(III) trichloride; methyl cyclohexane In 1,2-dichloro-ethane at 20℃; for 1h;	61%
With hydrogenchloride In water at 250℃; under 37503.8 Torr; for 1h; Sealed tube; Inert atmosphere;	59%

: 100-52-7
benzaldehyde

: 19967-55-6
1-bromo-3-methyl-2-butanone

A: 563-80-4
3-methyl-butan-2-one

B: 3160-32-5
4-methyl-1-phenyl-1-penten-3-one

Conditions

Conditions	Yield
With tributylstibine at 50℃; for 9h;	A n/a B 98%

: 5508-40-7
4-methyl-N'-(3-methylbutan-2-ylidene)benzenesulfonohydrazide

: 563-80-4
3-methyl-butan-2-one

Conditions

Conditions	Yield
With silica gel; copper(II) nitrate In tetrachloromethane for 1h; Heating;	97%

: 598-75-4
3-methyl-2-butanol

: 563-80-4
3-methyl-butan-2-one

Conditions

Conditions	Yield
With water; dihydrogen peroxide; tetra(n-butyl)ammonium hydrogensulfate; sodium tungstate at 100℃; for 0.166667h; Oxidation; microwave irradiation;	94%
With potassium permanganate; Rexyn 101 H ion exchange resin In dichloromethane for 4.3h; Heating;	92%
In neat (no solvent) at 20℃; for 0.0666667h; Microwave irradiation;	89%

: 66-25-1
hexanal

: 19967-55-6
1-bromo-3-methyl-2-butanone

A: 563-80-4
3-methyl-butan-2-one

B: 122657-49-2
3-methyl-4E-decen-3-one

Conditions

Conditions	Yield
With tributylstibine at 90℃; for 8h;	A n/a B 94%

: 930-96-1
3-bromo-2-thiophenecarboxaldehyde

: 19967-55-6
1-bromo-3-methyl-2-butanone

A: 563-80-4
3-methyl-butan-2-one

B: 122657-50-5
1-(3-bromo-2-thiophenyl)-4-methyl-1E-penten-3-one

Conditions

Conditions	Yield
With tributylstibine at 70℃; for 5h;	A n/a B 92%

: 617-67-4
3-methyl-butan-2-one semicarbazone

: 563-80-4
3-methyl-butan-2-one

Conditions

Conditions	Yield
With (Bu4N)2S2O8 In 1,2-dichloro-ethane at 80℃; for 1.5h; oxidative cleavage;	92%
With potassium carbonate In water at 9.9℃; Kinetics; Mechanism; Thermodynamic data; E(activ.), ΔG(excit.), ΔH(excit.), ΔS(excit.); other temperatures;

: 10473-14-0
3-methyl-3-buten-2-ol

: 563-80-4
3-methyl-butan-2-one

Conditions

Conditions	Yield
With diiron nonacarbonyl In benzene at 40 - 50℃; for 2.5h;	90%
With triiron dodecarbonyl at 25 - 30℃; for 2h; Irradiation;	88%
With sulfuric acid at 100℃;

molybdenum naphthenate: molybdenum naphthenate

: 7732-18-5
water

: 563-46-2
2-Methyl-1-butene

: 563-80-4
3-methyl-butan-2-one

Conditions

Conditions	Yield
With tert.-butylhydroperoxide	90%

: 630-19-3
pivalaldehyde

: 563-80-4
3-methyl-butan-2-one

Conditions

Conditions	Yield
With fluoroboric acid Rearrangement;	100%
With gallium(III) trichloride; methyl cyclohexane In 1,2-dichloro-ethane at 20℃; for 1h;	61%
With hydrogenchloride In water at 250℃; under 37503.8 Torr; for 1h; Sealed tube; Inert atmosphere;	59%

3-Methyl-2-butanone Chemical Properties

Molecular Structure of 3-Methyl-2-butanone (CAS NO.563-80-4):

Empirical Formula: C₅H₁₀O
Molecular Weight: 86.1323
IUPAC Name: 3-methylbutan-2-one
Synonyms of 3-Methyl-2-butanone (CAS NO.563-80-4): 2-Acetyl propane ; 2-Acetylpropane ; 2-Methyl-3-butanone ; 3-Methyl-2-butanone ; AI3-24194 ; Caswell No. 555A ; EINECS 209-264-3 ; EPA Pesticide Chemical Code 044104 ; Isopropyl methyl ketone ; Ketone, isopropyl methyl ; MIPK ; Methyl butanone-2 ; Methylbutanone (VAN) ; NSC 9379
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 1
Polar Surface Area: 17.07Å²
Index of Refraction: 1.38
Molar Refractivity: 25.2 cm³
Molar Volume: 108.5 cm³
Surface Tension: 21.4 dyne/cm
Density: 0.793 g/cm³
Enthalpy of Vaporization: 31.92 kJ/mol
Boiling Point: 78.3 °C at 760 mmHg
Vapour Pressure: 93.3 mmHg at 25°C
Melting point: −92 °C(lit.)
EINECS: 209-264-3
Product Categories: Industrial/Fine Chemicals; Organics; ketone
InChI
InChI=1/C5H10O/c1-4(2)5(3)6/h4H,1-3H3
Smiles
C(C(C)=O)(C)C

3-Methyl-2-butanone Uses

3-Methyl-2-butanone (CAS NO.563-80-4) is mainly used as a solvent and otherwise it also can be used as dye intermediates, synthesis of medicine, pesticide, mineral processing and other industries.

3-Methyl-2-butanone Production

By Adding Bromine into tert-AMYL ALCOHOL to get the 2,3-dibromo-2-methylbutane.And then adding WATER to return backflow for 3-5hours till the hydrolyze completely.Then we can get the 3-Methyl-2-butanone (CAS NO.563-80-4).

3-Methyl-2-butanone Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	200mg/kg (200mg/kg)	"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4737, 1982.
mouse	LD50	oral	2572mg/kg (2572mg/kg)	Toxicology Letters. Vol. 30, Pg. 13, 1986.
rabbit	LD50	skin	6350mg/kg (6350mg/kg)	Food and Cosmetics Toxicology. Vol. 16, Pg. 819, 1978.
rat	LCLo	inhalation	5700ppm/4H (5700ppm)	Toxicology and Applied Pharmacology. Vol. 28, Pg. 313, 1974.
rat	LD50	intraperitoneal	800mg/kg (800mg/kg)	"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4737, 1982.
rat	LD50	oral	148mg/kg (148mg/kg)	Shell Chemical Company. Unpublished Report. Vol. -, Pg. 7, 1961.

3-Methyl-2-butanone Safety Profile

Hazard Codes: F
Risk Statements: 11
R11:Highly flammable.
Safety Statements: 9-16-33
S9:Keep container in a well-ventilated place.
S16:Keep away from sources of ignition.
S33:Take precautionary measures against static discharges.
RIDADR: UN 2397 3/PG 2
WGK Germany: 1
RTECS: EL9100000
Hazard Note: Highly Flammable
HazardClass: 3
PackingGroup: II
HS Code: 29141990

3-Methyl-2-butanone Specification

3-Methyl-2-butanone (CAS NO.563-80-4) is a highly flammable liquid ketone, so you should keep it far away from fire. besides, it will explosive when mixed with combustible material.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 563-80-4