- Novel HIV reverse transcriptase inhibitors
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The invention is related to compounds of Formula (I), (II), or (III): or a pharmaceutically acceptable salt, solvate, ester, and/or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.
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Page/Page column 107
(2008/06/13)
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- MGluR5 modulators I
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The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.
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Page/Page column 26
(2008/06/13)
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- PYRIDAZINES XXIV. APPLICATION OF RADICALIC ETHOXYCARBONYLATION TO THE SYNTHESIS OF PYRIDAZINE MONO- AND POLYCARBOXYLIC ACID ESTERS
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Reactivity of pyridazines 1, 2, 3, 16 towards ethoxycarbonylradical (generated by redox decomposition of oxyhydroperoxyde of ethylpyruvate) was studied.Application of this type of homolytic substitution for synthesis of hitherto not accessible pyridazine carboxylic acid esters 6, 8, 9, 12, 13, 14, 15, 17 is demonstrated.In addition improved synthesis of diethyl 4,5-pyridazinedicarboxylate (5) is proposed.
- Heinisch, Gottfried,Loetsch, Gerhard
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p. 1199 - 1206
(2007/10/02)
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