39123-39-2

Basic information

• Product Name: ETHYL 4-PYRIDAZINECARBOXYLATE
• Synonyms: ethyl pyridazine-4-carboxylate;4-Pyridazinecarboxylic acid, ethyl ester
• CAS NO: 39123-39-2
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.15
• Mol File: 39123-39-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 290.915 °C at 760 mmHg
• Flash Point: 129.741 °C
• Appearance: /
• Density: 1.168 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ETHYL 4-PYRIDAZINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-PYRIDAZINECARBOXYLATE(39123-39-2)
• EPA Substance Registry System: ETHYL 4-PYRIDAZINECARBOXYLATE(39123-39-2)

Safety Data

• Hazardous Substances Data: 39123-39-2(Hazardous Substances Data)

Usage

General Description

Ethyl 4-pyridazinecarboxylate is a chemical compound with the molecular formula C8H8N2O2. It is a derivative of pyridazine, which is a six-membered aromatic heterocycle with two nitrogen atoms. Ethyl 4-pyridazinecarboxylate is commonly used as an intermediate in the synthesis of pharmaceuticals and agricultural chemicals. It has been reported to exhibit various biological activities, including antifungal, antibacterial, and anti-inflammatory properties. The compound is also used as a building block for the development of novel chemical entities with potential therapeutic applications. Overall, Ethyl 4-pyridazinecarboxylate is an important chemical intermediate with diverse industrial and pharmaceutical uses.

Upstream product

• 50681-25-9 pyridazine-4-carboxylic acid 
• 64-17-5 ethanol 
• 289-80-5 1,2-diazine 
• 617-35-6 2-oxo-propionic acid ethyl ester 

Downstream Products

• 86839-80-7 5-(2,6-Dichloro-benzoyl)-pyridazine-4-carboxylic acid 
• 86839-79-4 5-(3,4-Dichloro-benzoyl)-pyridazine-4-carboxylic acid 
• 86839-76-1 5-(4-Bromo-benzoyl)-pyridazine-4-carboxylic acid 
• 86839-77-2 5-(3-Chloro-benzoyl)-pyridazine-4-carboxylic acid 
• 86839-78-3 5-(2-Fluorobenzoyl)-4-pyridazinecarboxylic Acid 
• 124436-43-7 N'-[1-Pyridazin-4-yl-eth-(E)-ylidene]-hydrazinecarbodithioic acid methyl ester 
• 50901-43-4 4-hydroxymethylpyridazine 
• 86839-74-9 5-(3,4-Dichloro-benzoyl)-pyridazine-4-carboxylic acid ethyl ester 
• 75722-56-4 N-(o-aminophenyl)pyridazine-4-carboxamide 
• 75722-63-3 NN'-bis(pyridazine-4-carbonyl)-o-phenylenediamine 
• 86839-73-8 5-(2-Fluoro-benzoyl)-pyridazine-4-carboxylic acid ethyl ester 
• 86839-71-6 5-(4-Bromo-benzoyl)-pyridazine-4-carboxylic acid ethyl ester 
• 86839-72-7 5-(3-Chloro-benzoyl)-pyridazine-4-carboxylic acid ethyl ester 
• 86839-75-0 5-(2,6-Dichloro-benzoyl)-pyridazine-4-carboxylic acid ethyl ester 

Relevant articles and documents

Novel HIV reverse transcriptase inhibitors

The invention is related to compounds of Formula (I), (II), or (III): or a pharmaceutically acceptable salt, solvate, ester, and/or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.

PYRIDAZINES XXIV. APPLICATION OF RADICALIC ETHOXYCARBONYLATION TO THE SYNTHESIS OF PYRIDAZINE MONO- AND POLYCARBOXYLIC ACID ESTERS

Reactivity of pyridazines 1, 2, 3, 16 towards ethoxycarbonylradical (generated by redox decomposition of oxyhydroperoxyde of ethylpyruvate) was studied.Application of this type of homolytic substitution for synthesis of hitherto not accessible pyridazine carboxylic acid esters 6, 8, 9, 12, 13, 14, 15, 17 is demonstrated.In addition improved synthesis of diethyl 4,5-pyridazinedicarboxylate (5) is proposed.