CHALCONE Chemical Properties
Chalcone's Molecular formula: C15H12O
Chalcone's Molar mass: 208.26 g mol-1
Density: 1.071 g/cm3
Melting point: 55–57 °C
Boiling point: 345-348 °C
Other names: Chalcone;Chalkone;Benzylideneacetophenone;Phenyl styryl ketone
Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.
CHALCONE Uses
Chalcones show antibacterial, antifungal, antitumor and anti-inflammatory properties.
Some chalcones demonstrated the ability to block voltage-dependent potassium channels.
Chalcones are also intermediates in the biosynthesis of flavonoids, which are substances widespread in plants and with an array of biological activities.
Chalcones are also intermediates in the Auwers synthesis of flavones.
CHALCONE Production
Chalcones can be prepared by an aldol condensation between a benzaldehyde and an acetophenone in the presence of sodium hydroxide as a catalyst.
CHALCONE Toxicity Data With Reference
1. | | ivn-mus LD50:56 mg/kg | | CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#04476 . |
CHALCONE Consensus Reports
Reported in EPA TSCA Inventory.
CHALCONE Safety Profile
Poison by intravenous route. See also
KETONES. When heated to decomposition it emits acrid smoke and irritating fumes.
CHALCONE Standards and Recommendations
DOT Classification: 3; Label: Flammable Liquid