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Cefradine

  • Name Cefradine
  • EINECS254-137-8
  • CAS No. 38821-53-3
  • Density1.47 g/cm3
  • PSA138.03000
  • LogP1.37770
  • SolubilitySoluble in water
  • Melting Point140-142 °C
  • FormulaC16H19N3O4S
  • Boiling Point693.1 °C at 760 mmHg
  • Molecular Weight349.411
  • Flash Point373 °C
  • Transport InformationN/A
  • AppearanceSolid
  • Safety26-36
  • Risk Codes36/37/38-42/43-20/21/22
  • Molecular Structure
    Molecular Structure of 38821-53-3 (Cefradine)
  • Hazard SymbolsHarmfulXn, IrritantXi
  • SynonymsHarmfulXn, IrritantXi
  • Article Data12

Cefradine Chemical Properties

Product Name: (6R-(6alpha,7))-((Amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: (6r-(6alpha,7))-((amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;CEPHRADINE;CEPHRADINE HYDRATE;CEFRADIN;CEFRADINE;(6r-(6-alpha,7-beta(r*)))-ien-1-ylacetyl)amino)-3-methyl-8-oxo;(6r-6alpha,7beta(r*)))-ien-1-ylacetyl)amino)-3-methyl-8-ox;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((amino-1,4-cyclohexad 
Product Categories: Drug bulk
The Molecular formula of Sefril (CAS NO.38821-53-3): C16H21N3O5S
The Molecular Weight of Sefril (CAS NO.38821-53-3): 367.42 g/mol
Molecular Structure of Sefril (CAS NO.38821-53-3):   
EINECS: 254-137-8
Melting point: 140-142 deg C
storage temp.: Store at 0-5°C
Appearance: Solid
Density: 1.47 g/cm3
Flash Point: 373 °C
 Index of Refraction: 1.683
Surface Tension: 74.6 dyne/cm
Enthalpy of Vaporization: 110.65 kJ/mol
Boiling Point: 693.1 °C at 760 mmHg
Vapour Pressure of Sefril (CAS NO.38821-53-3): 4.85E-21 mmHg at 25 °C
 

Cefradine Toxicity Data With Reference

1.    

orl-wmn TDLo:5 mg/kg:SKN

    CUTIBC    CUTIS; Cutaneous Medicine for the Practitioner. 38 (1986),58.
2.    

orl-mus LD50:3549 mg/kg

    NKRZAZ    Chemotherapy (Tokyo). 23 (1975),37.
3.    

ipr-mus LD50:597 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.
4.    

scu-mus LD50:2890 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.
5.    

ivn-mus LD50:3539 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.

Cefradine Safety Profile

Moderately toxic by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects: dermatitis. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
The Hazard Codes of Sefril (CAS NO.38821-53-3):IrritantXi,HarmfulXn
The Risk Statements information of SEFRIL(38821-53-3): 20/21/22-36/37/38-42/43
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R42/43:May cause sensitization by inhalation and skin contact.
The Safety Statements information of Sefril (CAS NO.38821-53-3): 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing. 
RTECS XI0336000

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