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Cas Database |
| Name |
Cervagem |
EINECS | N/A |
| CAS No. | 64318-79-2 | Density | 1.08g/cm3 |
| PSA | 83.83000 | LogP | 3.97560 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C23H38 O5 | Boiling Point | 510.5oC at 760 mmHg |
| Molecular Weight | 394.552 | Flash Point | 163.9oC |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion, subcutaneous, intravenous, and intravaginal routes. Human reproductive effects by intravaginal route: abortion, changes in the uterus, cervix, and vagina. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See other prostaglandin entries. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
16,16-Dimethyl-trans-D2-PGE methyl ester;16,16-Dimethyl-trans-D2-PGE1 methyl ester; 16,16-Dimethyl-trans-D2-prostaglandin E1 methyl ester; Carprost; Cergem;Cervagem; Cervageme; Gemeprost; Methyl 16,16-dimethyl-trans-D2-PGE1; ONO 802; Preglandin; SC37681; trans-2,3-Didehydro-16,16-dimethyl PGE1 methyl ester |
Article Data | 3 |
Cervagem Chemical Properties
Chemistry informtion about Cervagem (CAS NO.64318-79-2) is:
IUPAC Name: Methyl (E)-7-[(1s,2s,3s)-3-Hydroxy-2-[(Z,3r)-3-Hydroxy-4,4-Dimethyloct-1-Enyl]-5-Oxocyclopentyl]Hept-2-Enoate
Synonyms: Gemeprost ; 16,16-Dimethyl-Trans-Δ2-Pge Methyl Ester ; 16,16-Dimethyl-Trans-Δ2-Pge1 Methyl Ester ; 16,16-Dimethyl-Trans-Δ2-Prostaglandin E1 Methyl Ester ; Carprost ; Cergem ; Cervagem ; Cervageme
MF: C23H38O5
MW: 394.544820 g/mol
EINECS: 264-775-9
Density: 1.08 g/cm3
Flash Point: 163.9 °C
Boiling Point: 510.5 °C at 760 mmHg
Vapour Pressure: 1.47E-12 mmHg at 25°C
Enthalpy of Vaporization: 89.95 kJ/mol
Following is the molecular structure of Cervagem (CAS NO.64318-79-2) is:
Cervagem Toxicity Data With Reference
Toxic information about Cervagem (CAS NO.64318-79-2) is:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravaginal | 36mg/kg (36mg/kg) | gastrointestinal: "hypermotility, diarrhea" | Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982. |
| mouse | LD50 | intravenous | 29500ug/kg (29.5mg/kg) | behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: respiratory depression | Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982. |
| mouse | LD50 | oral | 59mg/kg (59mg/kg) | behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: respiratory depression gastrointestinal: "hypermotility, diarrhea" | Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982. |
| mouse | LD50 | subcutaneous | 32500ug/kg (32.5mg/kg) | behavioral: altered sleep time (including change in righting reflex) lungs, thorax, or respiration: respiratory depression | Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982. |
| rat | LD50 | intravaginal | 32500ug/kg (32.5mg/kg) | gastrointestinal: "hypermotility, diarrhea" | Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982. |
| rat | LD50 | intravenous | 28600ug/kg (28.6mg/kg) | behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: respiratory depression | Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982. |
| rat | LD50 | oral | 56500ug/kg (56.5mg/kg) | behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: respiratory depression gastrointestinal: "hypermotility, diarrhea" | Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982. |
| rat | LD50 | subcutaneous | 22600ug/kg (22.6mg/kg) | behavioral: altered sleep time (including change in righting reflex) lungs, thorax, or respiration: respiratory depression | Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982. |
Cervagem Safety Profile
Poison by ingestion, subcutaneous, intravenous, and intravaginal routes. Human reproductive effects by intravaginal route: abortion, changes in the uterus, cervix, and vagina. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See other prostaglandin entries.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III
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