The Journal of Lipid Research (JLR) focuses on the science of lipids in health and disease. The Journal emphasizes lipid function and the biochemical and genetic regulation of lipid metabolism. In addition, JLR publishes manuscripts on patient-oriented and epidemiological research relating to altered lipid metabolism, including modification of dietary lipids. The JLR aims to be on the forefront of the emerging areas of genomics, proteomics, and lipidomics as they relate to lipid metabolism and function. 

The JLR covers biochemistry, cell biology, molecular biology, structural biology, genetics, genomics, immunology, metabolism, nutrition and clinical science as they relate to lipids. The following are representative areas covered in the Journal: Adipose tissue metabolism; Animal models of lipid abnormalities; Antioxidants and lipid peroxidation; Apolipoproteins, lipid transport and metabolism; Atherogenesis; Bile acids and bile acid metabolism; Biophysics; Brain lipids; Cell signaling; synthesis and trafficking; Clinical studies elucidating lipid dysfunction; Dietary lipids and disease prevention; Eicosanoids; Fatty acid binding proteins and metabolism; Genomics of lipids; Inborn errors in lipid metabolism; Lipases in lipid processing; Lipid enzymes; Lipidomics; Lipid micelle structure and organization; Lipid transfer proteins; Lipoproteins; Membrane lipids and structure; Model systems; Modified lipoproteins; Neutral lipids; Oxidized LDL; Oxysterols and sterol metabolism; Phospholipids and phospholipases; Protein-lipid interactions; Receptors for lipids; Sphingolipids.

JLR publishes original articles, including methods papers and short communications, as well as reviews. Articles describing patient-oriented research are also encouraged. Because JLR has worldwide distribution, contributions are encouraged from investigators in all countries, but articles must be submitted in clear and concise English.