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Basic information

  • Name:
  • D(-)-Salicin

  • CAS No.:
  • 138-52-3

  • Molecular Structure:
  • Formula:
  • C13H18O7
  • Molecular Weight:
  • 286.28
  • Deleted CAS:
  • 30370-90-2
  • Synonyms:
  • Salicyl alcohol glucoside;Salicine;Salicoside;a-D-Glucopyranoside,2-(hydroxymethyl)phenyl;Benzyl alcohol, o-hydroxy-, o-glucoside;2-(Hydroxymethyl)-phenyl-beta-D-glucopyranoside;Saligenin-.beta.-D-glucopyranoside;(2R,3R,4R,5S,6S)-2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol;2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol;White willow bark P. E.;α-hydroxy-o-tolyl β-D-glucopyranoside;Salicylaldehyde glycosides;Salicin;White Willow Bark Extract;
  • EINECS:
  • 205-331-6
  • Density:
  • 1.504 g/cm3
  • Melting Point:
  • 197-200 °C
  • Boiling Point:
  • 549.1 °C at 760 mmHg
  • Flash Point:
  • 285.9 °C
  • Solubility:
  • 36 g/L (15°C), 250 g/L (60 °C) in water
  • Appearance:
  • white crystals or powder
  • Hazard Symbols:
  • IrritantXi
  • Risk Codes:
  • 43
  • Safety Description:
  • 36/37-24/25 Details

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Chemistry

IUPAC Name: (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
Synonyms of D(-)-Salicin (CAS NO.138-52-3): 2-(Hydroxymethyl)phenyl beta-D-glucopyranoside ; Benzyl alcohol, o-hydroxy-, o-glucoside ; Salicine ; Salicoside ; Salicyl alcohol glucoside ; o-(Hydroxymethyl)phenyl beta-D-glucopyranoside ; B-D-Glucopyranoside, 2-(hydroxymethyl)phenyl ; Salicin (6CI,8CI)
CAS NO: 138-52-3
Molecular Formula: C13H18O7
Molecular Weight: 286.28
Molecular Structure:
EINECS: 205-331-6
H bond acceptors: 7
H bond donors: 5
Freely Rotating Bonds: 9
Polar Surface Area: 64.61 Å2
Index of Refraction: 1.638
Molar Refractivity: 68.41 cm3
Molar Volume: 190.3 cm3
Surface Tension: 70.1 dyne/cm
Density: 1.504 g/cm3
Flash Point: 285.9 °C
Enthalpy of Vaporization: 87.22 kJ/mol
Boiling Point: 549.1 °C at 760 mmHg
Vapour Pressure: 6.85E-13 mmHg at 25°C
Melting point 197-200°C
Alpha: -61.5 º (c=5, water)
Water solubility: 36 g/L (15°C), 250 g/L (60 °C)
Storage temp: Store at RT.
Appearance: white crystals or powder
Stability: Stability Stable, but light sensitive. Incompatible with strong oxidizing agents.
Product Categories of D(-)-Salicin (CAS NO.138-52-3): Sugars, Carbohydrates & Glucosides;Biochemistry;Glucose;Glycosides;Sugars;Natural Plant Extract;Herbs & Natural Remedies

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD intraperitoneal > 500mg/kg (500mg/kg)   "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 6, Pg. 63, 1954.

Safety Profile

Safety Information of  D(-)-Salicin (CAS NO.138-52-3):
The Hazard Codes: Xi
The Risk Statements: 43
43:  May cause sensitization by skin contact 
The Safety Statements: 36/37-24/25
24/25: Avoid contact with skin and eyes 
36/37: Wear suitable protective clothing and gloves
WGK Germany: 3
RTECS: LZ5901700
F: 3-10
HS Code: 29389090  

Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. 
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Store in a tightly closed container.

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