Basic information
- Name:
D-Histidine
- CAS No.:
351-50-8
- Molecular Structure:

- Formula:
- C6H9N3O2
- Molecular Weight:
- 209.63
- Synonyms:
- Histidine,D- (8CI);(R)-Histidine;H-D-His-OH;
- EINECS:
- 206-513-8
- Density:
- 1.423 g/cm3
- Melting Point:
- 280-290 °C (dec.)
- Boiling Point:
- 458.9 °C at 760 mmHg
- Flash Point:
- 231.3 °C
- Appearance:
- white crystalline powder
- Hazard Symbols:
Xn- Safety Description:
- 22-24/25-36/37-26 Details
- particular:
- particular
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Specification
The D-Histidine, with its cas register number 351-50-8, has the IUPAC name of (2R)-2-amino-3-(1H-imidazol-5-yl)propanoic acid. And it also has other names as h-d-his-oh; histidine, d-; d-alpha-amino-beta-imidazolepropionic acid; d-alpha-amino-beta-(4-imidazolyl)propionic acid; d-2-amino-3-(4-imidazolyl)propionic acid; d-his-oh; d-histidine; d-his.
The physical characteristics of this chemical could be summarized as: (1)ACD/LogP: -1.27; (2)ACD/LogD (pH 5.5): -4.54; (3)ACD/LogD (pH 7.4): -3.82; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 5; (9)#H bond donors: 4; (10)#Freely Rotating Bonds: 4; (11)Polar Surface Area: 47.36; (12)Index of Refraction: 1.614; (13)Molar Refractivity: 38.01 cm3; (14)Molar Volume: 108.9 cm3; (15)Polarizability: 15.07 ×10-24 cm3; (16)Surface Tension: 79.6 dyne/cm; (17)Density: 1.423 g/cm3; (18)Flash Point: 231.3 °C; (19)Enthalpy of Vaporization: 75.79 kJ/mol; (20)Boiling Point: 458.9 °C at 760 mmHg; (21)Vapour Pressure: 3.25E-09 mmHg at 25°C.
This is a kind of white crystalline powder, and its water Solubility is 42 g/L (25 ºC). Being a kind of harmful chemical, it may cause damage to health. And it is harmful by swallowed and is very toxic by inhalation, in contact with skin or if swallowed. Besides, it is irritating to eyes and respiratory system. You could also go to WGK Germany 3 to obtain more safety information. When store it, it should be kept in room temperature.
D-Histidine is commonly used as intermediates of fine chemicals and pharmaceutical. As to its product categories, there are various, including amino acid derivatives; histidine [his, h]; amino acids and derivatives; alpha-amino acids; amino acids; biochemistry; amino acids.
In addition, you could refer to the following information to obtain the molecular structure:
SMILES:O=C(O)[C@H](N)Cc1cncn1
InChI:InChI=1/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m1/s1
InChIKey:HNDVDQJCIGZPNO-RXMQYKEDBE

