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Isoproterenol hydrochloride

  • Name Isoproterenol hydrochloride
  • EINECS200-089-8
  • CAS No. 949-36-0
  • Density1.199g/cm3
  • PSA72.72000
  • LogP2.32210
  • SolubilityN/A
  • Melting Point165-175 °C (dec.)(lit.)
  • FormulaC11H17 N O3 . Cl H
  • Boiling Point417.5°Cat760mmHg
  • Molecular Weight247.722
  • Flash Point179.7°C
  • Transport InformationN/A
  • AppearanceN/A
  • SafetyPoison by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Human systemic effects: blood pressure elevation. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl.
  • Risk Codes36/37/38
  • Molecular Structure
    Molecular Structure of 949-36-0 (ISOPROTERENOL HYDROCHLORIDE)
  • Hazard Symbols
  • Synonyms
  • Article Data6

Isoproterenol hydrochloride Chemical Properties

Empirical Formula: C11H18ClNO3
Molecular Weight: 247.7185 g/mol
EINECS: 200-089-8
Flash Point: 179.7 °C
Enthalpy of Vaporization: 70.73 kJ/mol
Boiling Point: 417.5 °C at 760 mmHg
Vapour Pressure: 1.02E-07 mmHg at 25 °C
Melting point: 165-175 °C (dec.)(lit.)
Structure of Isoproterenol hydrochloride (CAS NO.949-36-0):
               
Systematic Name of Isoproterenol hydrochloride (CAS NO.949-36-0): 4-[1-Hydroxy-2-(isopropylamino)ethyl]benzene-1,2-diol hydrochloride
Product Categories of Isoproterenol hydrochloride (CAS NO.949-36-0): Drug / Therapeutic Agenta;Reproductive Effect

Isoproterenol hydrochloride Toxicity Data With Reference

1.    

dns-mus-ipr 10 µmol/kg

    CNREA8    Cancer Research. 39 (1979),2751.
2.    

orl-hmn TDLo:250 µg/kg:BPR

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 92 (1948),108.
3.    

ipr-rat LD50:303 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),74.
4.    

scu-rat LD50:435 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),74.
5.    

ivn-rat LD50:24,040 µg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),74.
6.    

orl-mus LD50:2420 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 13 (1963),51.
7.    

ipr-mus LD50:250 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),74.
8.    

scu-mus LD50:298 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),74.
9.    

ivn-mus LD50:23,500 µg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6t

Isoproterenol hydrochloride Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Human systemic effects: blood pressure elevation. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl.
Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.

Isoproterenol hydrochloride Specification

 Isoproterenol hydrochloride ,its cas register number is 949-36-0. It also can be called 4-[1-Hydroxy-2-(isopropylamino)ethyl]-1,2-benzenediol hydrochloride (1:1) ; Pyrocatechol, 4-(1-hydroxy-2-(isopropylamino)ethyl)-, hydrochloride ; 3,4-Dihydroxy-.alpha.-[(isopropylamino)methyl]benzyl alcohol hydrochloride ;and 1,2-Benzenediol, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1) .

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