- Lycorine hydrochloride
- Lycorine hydrochloride
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| Name |
Lycorine hydrochloride |
EINECS | N/A |
| CAS No. | 2188-68-3 | Density | N/A |
| PSA | 62.16000 | LogP | 0.68650 |
| Solubility | N/A | Melting Point |
210-212oC |
| Formula | C16H17NO4.HCl | Boiling Point | 477.4 °C at 760 mmHg |
| Molecular Weight | 323.776 | Flash Point | 242.5 °C |
| Transport Information | UN 2811 6.1/PG 3 | Appearance | fine crystal powder. |
| Safety | 45 | Risk Codes | 25 |
| Molecular Structure |
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Hazard Symbols |
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| Synonyms |
1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride, (1S,2S,12bS,12cS)- (9CI);Galanthan-1,2-diol, 3,12-didehydro-9,10-[methylenebis(oxy)]-, hydrochloride, (1a,2b)-;Lycoran-1a,2b-diol, 3,3a-didehydro-, hydrochloride (8CI);Licorin hydrochloride; |
Lycorine hydrochloride Chemical Properties
Molecular Structure:
Molecular Formula: C16H18ClNO4
Molecular Weight: 323.7714
Systematic Name: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol hydrochloride (1:1)
Synonyms of Lycorine hydrochloride (CAS NO.2188-68-3): Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- ; Licorin hydrochloride ; Lycorine HCl ; Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-, hydrochloride
CAS NO: 2188-68-3
Classification Code: Peptidyl transferaseCell Signaling and Neuroscience ; Enzyme Inhibitors by Enzyme ; Gene Regulation and Expression ; P to ; RNA-Protein Translation Inhibitors
Flash Point: 242.5 °C
Enthalpy of Vaporization: 78.09 kJ/mol
Boiling Point: 477.4 °C at 760 mmHg
Vapour Pressure: 6.37E-10 mmHg at 25°C
Lycorine hydrochloride Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 117mg/kg (117mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958. | |
| mouse | LD50 | intravenous | 123mg/kg (123mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: NAUSEA OR VOMITING | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958. |
| mouse | LD50 | oral | 230mg/kg (230mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958. |
Lycorine hydrochloride Safety Profile
Hazard Codes of Lycorine hydrochloride (CAS NO.2188-68-3): 
T
Risk Statements: 25
R25: Toxic if swallowed.
Safety Statements: 45
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3
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