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| Name |
Methylphenidate hydrochloride |
EINECS | 206-065-3 |
| CAS No. | 298-59-9 | Density | 1.07g/cm3 |
| PSA | 38.33000 | LogP | 3.21610 |
| Solubility | N/A | Melting Point |
224 - 226oC |
| Formula | C14H19NO2.HCl | Boiling Point | 327.6 °C at 760 mmHg |
| Molecular Weight | 269.771 | Flash Point | 152 °C |
| Transport Information | UN 3249 | Appearance | white crystalline powder |
| Safety | 22-26-36 | Risk Codes | 22-42 |
| Molecular Structure |
|
Hazard Symbols |
 Xn
|
| Synonyms |
2-Piperidineaceticacid, a-phenyl-, methyl ester,hydrochloride (6CI,8CI,9CI);Centedrin;Centedrine;Concerta;Medikinet;Metadate CD;Methyl a-phenyl-2-piperidineacetate hydrochloride;NSC 169868;Ritalin;Ritalin Hydrochloride;Ritalin SR; |
Article Data | 15 |
Methylphenidate hydrochloride Chemical Properties
Molecular Formula: C14H20ClNO2 
Formula Weight: 269.77
Melting Point: 224 - 226 °C
Flash Point of RITALIN HYDROCHLORIDE (298-59-9): 152 °C
Boiling Point of RITALIN HYDROCHLORIDE (298-59-9): 327.6 °C at 760 mmHg
Vapour Pressure: 0.000199 mmHg at 25°C
Appearance: RITALIN HYDROCHLORIDE (298-59-9) is a white crystalline powder
Formula Weight: 269.77
Melting Point: 224 - 226 °C
Flash Point of RITALIN HYDROCHLORIDE (298-59-9): 152 °C
Boiling Point of RITALIN HYDROCHLORIDE (298-59-9): 327.6 °C at 760 mmHg
Vapour Pressure: 0.000199 mmHg at 25°C
Appearance: RITALIN HYDROCHLORIDE (298-59-9) is a white crystalline powder
Methylphenidate hydrochloride Uses
RITALIN HYDROCHLORIDE (298-59-9) is used as a controlled substance (stimulant).
Methylphenidate hydrochloride Toxicity Data With Reference
| 1. | otr-ham:emb 500 mg/L | ENMUDM Environmental Mutagenesis. 8 (Suppl 6)(1986),4. | ||
| 2. | orl-cld TDLo:32 mg/kg/6W-I:PSY | BIPCBF Biological Psychiatry. 20 (1985),1332. | ||
| 3. | orl-rat LD50:367 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,1972,264. | ||
| 4. | scu-rat LD50:170 mg/kg | CLDND* Compilation of LD50 Values of New Drugs .(J.R. MacDougal,Dept. of National Health and Welfare, Food and Drug Divisions,Ottawa, Ontario, Canada.: )1972,264. | ||
| 5. | orl-mus LD50:60 mg/kg | JMCMAR Journal of Medicinal Chemistry. 18 (1975),71. | ||
| 6. | ipr-mus LD50:167 mg/kg | JMCMAR Journal of Medicinal Chemistry. 14 (1971),1106. | ||
| 7. | scu-mus LD50:150 mg/kg | JMCMAR Journal of Medicinal Chemistry. 14 (1971),1106. | ||
| 8. | ivn-mus LDLo:40 mg/kg | KLWOAZ Klinische Wochenscrift. 32 (1954),445. |
Methylphenidate hydrochloride Safety Profile
Hazard Codes : Xn: Harmful
Risk Statements : 22: Harmful if swallowed
42: May cause sensitization by inhalation
Safety Statements : 22: Do not breathe dust
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
RIDADR : 3249
WGK Germany : 3
RTECS : TM3850000
HazardClass : 6.1(b)
PackingGroup : III
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: toxic psychosis. Mutation data reported. Used as a central nervous system stimulant. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Risk Statements : 22: Harmful if swallowed
42: May cause sensitization by inhalation
Safety Statements : 22: Do not breathe dust
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
RIDADR : 3249
WGK Germany : 3
RTECS : TM3850000
HazardClass : 6.1(b)
PackingGroup : III
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: toxic psychosis. Mutation data reported. Used as a central nervous system stimulant. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Methylphenidate hydrochloride Specification
Storage of RITALIN HYDROCHLORIDE (298-59-9): Keep container in a cool, well-ventilated area. Keep container tightly closed.