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Platiphillin

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Name

Platiphillin

EINECS N/A
CAS No. 480-78-4 Density 1.22g/cm3
PSA 76.07000 LogP 1.21060
Solubility N/A Melting Point 129°
Formula C18H27NO5 Boiling Point 539.6°Cat760mmHg
Molecular Weight 337.46 Flash Point 280.1°C
Transport Information N/A Appearance N/A
Safety A poison by intraperitoneal and intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 480-78-4 (platyphylline) Hazard Symbols Moderately toxic by ingestion.
Synonyms

480-78-4;

 

Platiphillin Chemical Properties

Product Name: Platyphylline
Synonyms: 1alpha,13S,15Z)-12-Hydroxy-1,2-dihydrosenecionan-11,16-dione ; [1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidenedodecahydro-6-hydroxy-5,6-dimethyl-, (3Z,5S,6R,9aS,14aR,14bR)-
CAS NO: 480-78-4
Molecular Formula of Platiphillin (CAS NO.480-78-4) : C18H27NO5
Molecular Weight of Platiphillin (CAS NO.480-78-4) : 337.4107
Molecular Structure of Platiphillin (CAS NO.480-78-4) :
EINECS: 207-558-6
Index of Refraction: 1.553
Surface Tension: 49.6 dyne/cm
Density: 1.22 g/cm3
Flash Point: 280.1 °C
Enthalpy of Vaporization: 93.95 kJ/mol
Boiling Point: 539.6 °C at 760 mmHg
Vapour Pressure: 6.81E-14 mmHg at 25°

Platiphillin Uses

Platifillin has holinoliticheskoe effect.

Platiphillin Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 577mg/kg (577mg/kg) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997.
mouse LD50 intravenous 105mg/kg (105mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"

BLOOD: "LYMPHOMA, INCLUDING HODGKIN'S DISEASE"
Research Today. Vol. 5, Pg. 53, 1949.
mouse LD50 oral 2573mg/kg (2573mg/kg) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997.
rat LD50 intraperitoneal 252mg/kg (252mg/kg)   Australian Journal of Experimental Biology and Medical Science. Vol. 46, Pg. 493, 1968.
rat LD50 intravenous 60mg/kg (60mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"

BLOOD: "LYMPHOMA, INCLUDING HODGKIN'S DISEASE"
Research Today. Vol. 5, Pg. 53, 1949.
rat LD50 oral 3100mg/kg (3100mg/kg) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997.

Platiphillin Safety Profile

A poison by intraperitoneal and intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.
RIDADR 1544
HazardClass 6.1(b)
PackingGroup III

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