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The Polyethoxylated fatty alcohols, with the CAS registry number 9002-92-0,is also known as Polyoxyethylene lauryl ether; Dodecyl polyglycol ether. It belongs to the product categories of Cell Lysis and Protein Extraction Reagents;Core Bioreagents;Research Essentials. This chemical's molecular formula is C12H25O.(C2H4O)n. What's more,Its systematic name is Ethoxylated lauryl alcohol.It is a liquid which is stable,combustible,incompatible with strong oxidizing agents.And it is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. It is suggested for use as emulsifier in cosmetics to add body and texture (humectant) and in household products.
Safety Information of Polyethoxylated fatty alcohols:
The Polyethoxylated fatty alcohols is harmful if swallowed and risk of serious damage to eyes .It is irritating to eyes, respiratory system and skin .In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.When you use it ,wear suitable protective clothing, gloves and eye/face protection and avoid contact with skin and eyes .
The toxicity data of Polyethoxylated fatty alcohols are as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | intravenous | 38mg/kg (38mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. |
guinea pig | LD50 | oral | 384mg/kg (384mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. |
mouse | LD50 | intraperitoneal | 160mg/kg (160mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. | |
mouse | LD50 | intraperitoneal | 160mg/kg (160mg/kg) | Drugs in Japan Vol. -, Pg. 1300, 1995. | |
mouse | LD50 | intravenous | 100mg/kg (100mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. | |
mouse | LD50 | intravenous | 100mg/kg (100mg/kg) | Toxicology and Applied Pharmacology. Vol. 7, Pg. 206, 1965. | |
mouse | LD50 | oral | 1170mg/kg (1170mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. | |
mouse | LD50 | oral | 1170mg/kg (1170mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. |
mouse | LD50 | oral | 3500mg/kg (3500mg/kg) | American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962. | |
mouse | LD50 | oral | 4940mg/kg (4940mg/kg) | American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962. | |
mouse | LD50 | subcutaneous | 792mg/kg (792mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. | |
mouse | LD50 | subcutaneous | 792300ug/kg (792.3mg/kg) | Drugs in Japan Vol. -, Pg. 1300, 1995. | |
rabbit | LD50 | intratracheal | > 15mg/kg (15mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. | |
rabbit | LD50 | intravenous | 36mg/kg (36mg/kg) | KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. |
rabbit | LD50 | parenteral | > 75mg/kg (75mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. | |
rat | LD50 | intraperitoneal | 125mg/kg (125mg/kg) | GASTROINTESTINAL: OTHER CHANGES | Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970. |
rat | LD50 | intravenous | 27mg/kg (27mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. | |
rat | LD50 | intravenous | 27mg/kg (27mg/kg) | Drugs in Japan Vol. -, Pg. 1300, 1995. | |
rat | LD50 | intravenous | 390mg/kg (390mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. | |
rat | LD50 | oral | 1gm/kg (1000mg/kg) | LIVER: FATTY LIVER DEGERATION GASTROINTESTINAL: OTHER CHANGES GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH | Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970. |
rat | LD50 | oral | 4150mg/kg (4150mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. | |
rat | LD50 | oral | 8600mg/kg (8600mg/kg) | Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965. | |
rat | LD50 | oral | 8600mg/kg (8600mg/kg) | Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965. | |
rat | LD50 | subcutaneous | 953mg/kg (953mg/kg) | Drugs in Japan Vol. -, Pg. 1300, 1995. | |
rat | LD50 | subcutaneous | 954mg/kg (954mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. |