Tosyl-L-glutamic acid

Base Information Edit

Chemical Name:Tosyl-L-glutamic acid
CAS No.:4816-80-2
Molecular Formula:C12H15NO6S
Molecular Weight:301.32
Hs Code.:2935009090
European Community (EC) Number:225-390-1
UNII:2HXU3N9FF3
DSSTox Substance ID:DTXSID301256419
Wikidata:Q76145316
Mol file:4816-80-2.mol

Synonyms:4816-80-2;(S)-2-(4-Methylphenylsulfonamido)pentanedioic acid;Tosyl-L-glutamic acid;N-Tosyl-L-glutamic acid;N-(p-Tolylsulphonyl)-L-glutamic acid;(+)-N-Tosyl-L-glutamic acid;(2S)-2-(4-methylbenzenesulfonamido)pentanedioic acid;C12H15NO6S;L-Glutamic acid, N-[(4-methylphenyl)sulfonyl]-;N-P-TOLYLSULFONYL-L-GLUTAMIC ACID;tosylglutamic acid;N-[(4-Methylphenyl)sulfonyl]-L-glutamic acid;2HXU3N9FF3;TOS-GLU-OH;N-((4-METHYLPHENYL)SULFONYL)-L-GLUTAMIC ACID;N-(p-Toluenesulfonyl)-L-glutamic acid;N-p-Tosyl-L-glutamic acid;EINECS 225-390-1;NSC-109186;2-(4-Methylphenylsulfonamido)pentanedioic acid;SCHEMBL255603;KKOZKXBAPIYWAT-JTQLQIEISA-N;DTXSID301256419;(+)-p-Toluenesulfonylglutamic Acid;MFCD00020545;(+)-toluene-p-sulphonylglutamic acid;AKOS010386362;AM81727;FD21349;AS-68614;CS-0310565;Nalpha-(4-methylbenzenesulfonyl)-L-glutamic acid;(S)-2-(4-Methylphenylsulfonamido)pentanedioicacid;A871943;J-500061;LEVOMETHADONE HYDROCHLORIDE IMPURITY F [EP IMPURITY];2-(4-Methylphenylsulfonamido)pentanedioic acid (Tos-L-Glu-OH);(2S)-2-(((4-METHYLPHENYL)SULFONYL)AMINO)PENTANEDIOIC ACID

Suppliers and Price of Tosyl-L-glutamic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-Tosyl-L-glutamic Acid
1g
$ 403.00

Usbiological
N-Tosyl-L-glutamic acid
100mg
$ 323.00

TRC
N-Tosyl-L-glutamicAcid
100mg
$ 45.00

TRC
N-Tosyl-L-glutamicAcid
250mg
$ 50.00

TRC
N-Tosyl-L-glutamicAcid
500mg
$ 65.00

Frontier Specialty Chemicals
N-p-Tosyl-L-glutamicacid 99%
100g
$ 58.00

Crysdot
(S)-2-(4-Methylphenylsulfonamido)pentanedioicacid 95+%
100g
$ 50.00

American Custom Chemicals Corporation
2-(TOLUENE-4-SULFONYLAMINO)PENTANEDIOIC ACID 95.00%
10G
$ 950.00

American Custom Chemicals Corporation
2-(TOLUENE-4-SULFONYLAMINO)PENTANEDIOIC ACID 95.00%
1G
$ 680.00

Alfa Aesar
N-(p-Toluenesulfonyl)-L-glutamic acid, 97%
500g
$ 326.00

Total 57 raw suppliers

Chemical Property of Tosyl-L-glutamic acid Edit

Chemical Property:

Appearance/Colour:white crystalline powder
Vapor Pressure:3.05E-12mmHg at 25°C
Melting Point:122-137 °C
Refractive Index:1.577
Boiling Point:534.2 °C at 760 mmHg
PKA:3.27±0.10(Predicted)
Flash Point:276.9 °C
PSA：129.15000
Density:1.421 g/cm³
LogP:2.06300
Storage Temp.:−20°C
Solubility.:DMSO, Methanol
XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:301.06200837
Heavy Atom Count:20
Complexity:447

Purity/Quality:

99% ^*data from raw suppliers

N-Tosyl-L-glutamic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC(CCC(=O)O)C(=O)O
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCC(=O)O)C(=O)O
Uses Protected L-Glutamic Acid.

Technology Process of Tosyl-L-glutamic acid

There total 6 articles about Tosyl-L-glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 55666-46-1
C₂₀H₃₁NO₆S

: 4816-80-2
N-tosyl-L-glutamic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1111/j.1747-0285.2011.01085.x

Reference yield: 93.0%

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 4816-80-2
N-tosyl-L-glutamic acid

Guidance literature:: With sodium hydroxide; In water; at 70 ℃;
DOI:10.1021/acs.orglett.5b00866

Reference yield: 92.0%

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 98-59-9
p-toluenesulfonyl chloride

: 4816-80-2
N-tosyl-L-glutamic acid

Guidance literature:: L-glutamic acid; p-toluenesulfonyl chloride; With sodium hydroxide; In water; at 70 ℃; for 1.5h;

With hydrogenchloride; In water; at 0 ℃; pH=3;