1-Naphthaleneethylamine

Base Information

• Chemical Name: 1-Naphthaleneethylamine
• CAS No.: 4735-50-6
• Molecular Formula: C12H13N
• Molecular Weight: 171.242
• Hs Code.: 2921499090
• European Community (EC) Number: 870-773-4
• DSSTox Substance ID: DTXSID90197115
• Nikkaji Number: J58.157G
• Wikidata: Q83070081
• Mol file: 4735-50-6.mol

Synonyms:4735-50-6;2-(1-naphthyl)ethanamine;2-(naphthalen-1-yl)ethanamine;1-NAPHTHALENEETHYLAMINE;1-Naphthaleneethanamine;2-naphthalen-1-ylethanamine;2-(1-Naphthyl)ethylamine;1-(2-Aminoethyl)naphthalene;2-(Naphthalen-1-Yl)Ethan-1-Amine;naphthylethylamine;1-Naphthaleneethanamine HCl;BRN 1101013;1-Naphthaleneethanamine (9CI);4-12-00-03213 (Beilstein Handbook Reference);(+/-)1-(1-Naphthyl) ethyl amine;2-naphthalen-1-ylethylamine;2-Naphthalen-1-yl-ethylamine;SCHEMBL134400;SCHEMBL718753;DTXSID90197115;MFCD01529866;AKOS000151385;AT29234;AC-29728;BS-13768;LS-94685;CS-0155981;EN300-39237;Z285143746

Chemical Property of 1-Naphthaleneethylamine

Chemical Property:

• Melting Point: 212-213 °C (decomp)
• Boiling Point: 313.9°Cat760mmHg
• PKA: 9.78±0.10(Predicted)
• Flash Point: 153°C
• PSA: 26.02000
• Density: 1.069g/cm³
• LogP: 3.04130
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 171.104799419
• Heavy Atom Count: 13
• Complexity: 155

Purity/Quality:

95% ^*data from raw suppliers

1-NaphthaleneethanamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2CCN

Technology Process of 1-Naphthaleneethylamine

There total 1 articles about 1-Naphthaleneethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

→ 2-naphthalen-1-yl-ethylamine (4735-50-6) + 3-cyclohexylpropan-1-amine (4361-44-8)

Guidance literature:

Reference yield: 84.0%

2-naphthalen-1-yl-ethylamine (4735-50-6) + phthalic anhydride (85-44-9) → N-[2-(2-(naphthalen-1-yl)ethyl)]isoindoline-1,3-dione (20062-23-1)

Guidance literature:

With boron tribromide; In toluene; Dean-Stark; Reflux;

DOI:10.1002/ejoc.201403617

Reference yield: 62.0%

2-naphthalen-1-yl-ethylamine (4735-50-6) + 4-methoxy-3-(4-(2,2,2-trichloroacetyl)piperazin-1-yl)benzene-1-sulfonyl chloride (219963-60-7) → 4-methoxy-N-(2-(naphthalen-1-yl)ethyl)-3-(4-(2,2,2-trichloroacetyl)piperazin-1-yl)benzenesulfonamide

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 25 ℃;

Downstream raw materials:

N-(2-[1]naphthyl-ethyl)-benzamide

N-<2-<5-methoxy-2-(phenylethynyl)phenyl>-1-methylethyl>-1-naphthaleneethanamine

[1-{[2-(tert-Butyl-dimethyl-silanyloxy)-3,3,3-trifluoro-1-isopropyl-propylcarbamoyl]-methyl}-4-(2-naphthalen-1-yl-ethylcarbamoyl)-2-oxo-1,2-dihydro-pyridin-3-yl]-carbamic acid benzyl ester

2-(2-bromophenyl)-N-[2-(naphth-1-yl)ethyl]acetamide

Refernces