4-(Trimethoxysilyl)aniline

Base Information

• Chemical Name: 4-(Trimethoxysilyl)aniline
• CAS No.: 33976-43-1
• Molecular Formula: C9H15NO3Si
• Molecular Weight: 213.308
• Hs Code.: 29319090
• European Community (EC) Number: 251-772-2
• DSSTox Substance ID: DTXSID30955554
• Nikkaji Number: J287.841K
• Wikidata: Q82935208
• Mol file: 33976-43-1.mol

Synonyms:4-(Trimethoxysilyl)aniline;33976-43-1;p-aminophenyltrimethoxysilane;4-trimethoxysilylaniline;aminophenyltrimethoxysilane;EINECS 251-772-2;MFCD00054700;4-aminophenyltrimethoxysilane;Benzenamine, 4-(trimethoxysilyl)-;C9H15NO3Si;SCHEMBL110157;Benzenamine,4-(trimethoxysilyl)-;DTXSID30955554;C38H54N8O11S;BBL103038;STL556847;AKOS008901163;Aminophenyltrimethoxysilane (contains all isomers)

Chemical Property of 4-(Trimethoxysilyl)aniline

Chemical Property:

• Vapor Pressure: 0.021mmHg at 25°C
• Melting Point: 60-62 °C
• Refractive Index: 1.502
• Boiling Point: 241.2 °C at 760 mmHg
• PKA: 4.17±0.10(Predicted)
• Flash Point: 99.7 °C
• PSA: 53.71000
• Density: 1.08 g/cm³
• LogP: 0.93510
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 213.08211987
• Heavy Atom Count: 14
• Complexity: 159

Purity/Quality:

98% min ^*data from raw suppliers

Aminophenyltrimethoxysilane ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CO[Si](C1=CC=C(C=C1)N)(OC)OC
• Uses: Aminophenyltrimethoxysilane is a useful intermediate for the preparation of aromatic silanes as high thermal stability coupling agents.

Technology Process of 4-(Trimethoxysilyl)aniline

There total 5 articles about 4-(Trimethoxysilyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N-dibenzyl-4-trimethoxysilylaniline → para-aminophenyltrimethoxysilane (33976-43-1)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃;

Reference yield:

tetramethylorthosilicate (681-84-5) + 2-(4-bromophenyl)-1,1,1,3,3,3-hexamethyldisilazane (5089-33-8) → para-aminophenyltrimethoxysilane (33976-43-1)

Guidance literature:

2-(4-bromophenyl)-1,1,1,3,3,3-hexamethyldisilazane; With magnesium; ethylene dibromide; In tetrahydrofuran; at 45 ℃; for 3h; Inert atmosphere; Reflux;

tetramethylorthosilicate; In tetrahydrofuran; at 25 ℃; for 0.5h; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; water; Inert atmosphere;

Reference yield:

C15H29NO3Si3 → para-aminophenyltrimethoxysilane (33976-43-1)

Guidance literature:

With sodium methylate; In methanol;

upstream raw materials:

tetramethylorthosilicate

2-(4-bromophenyl)-1,1,1,3,3,3-hexamethyldisilazane

4-bromo-aniline

Downstream raw materials:

4-pyridin-3-ylaniline

C₆₇H₈₃N₃O₄S₄Si

5-(4-aminophenyl)silatrane

Refernces

• 1、 -. "POLYAMIC ACID PRECURSOR COMPOUND INCLUDING SILICON, POLYAMIC ACID AND ORGANIC INORGANIC HYBRID POLYIMIDE FILM". Paragraph 0210-0214. . Retrieved 2018/04/14.
• 2、 -. "Diamino compounds and their production method". . . Retrieved 2008/06/13.