Laureth-5

Base Information

• Chemical Name: Laureth-5
• CAS No.: 3055-95-6
• Deprecated CAS: 136561-93-8
• Molecular Formula: C22H46O6
• Molecular Weight: 406.604
• Hs Code.: 2909499000
• European Community (EC) Number: 221-281-8
• DSSTox Substance ID: DTXSID1058632
• Nikkaji Number: J151.207B
• Wikipedia: Pentaethylene_glycol_monododecyl_ether
• Wikidata: Q3899231
• Mol file: 3055-95-6.mol

Synonyms:C12E5;C12EO5;dodecylpentaethylene glycol monoether;pentaethylene glycol mono-n-dodecyl ether;pentaethylene glycol monododecyl ether

Chemical Property of Laureth-5

Chemical Property:

• Appearance/Colour: solid
• Melting Point: 14.5-15.0 °C
• Refractive Index: 1.446～1.452(35℃/D)
• Boiling Point: 486.6 ºC at 760 mmHg
• PKA: 14.36±0.10(Predicted)
• Flash Point: 248.1 ºC
• PSA: 66.38000
• Density: 0.965 g/cm³
• LogP: 3.98260
• Storage Temp.: 2-8°C
• Solubility.: Do you have solubility information on this product that you woul
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 25
• Exact Mass: 406.32943918
• Heavy Atom Count: 28
• Complexity: 265

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pentaethylene Glycol Monododecyl Ether >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-36/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Uses -> Emulsifiers/Surfactants
• Canonical SMILES: CCCCCCCCCCCCOCCOCCOCCOCCOCCO

Technology Process of Laureth-5

There total 7 articles about Laureth-5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

oxirane (75-21-8,99932-75-9) + 1-dodecyl alcohol (112-53-8) → pentaethylene glycol mono-n-dodecyl ether (3055-95-6,9015-55-8)

Guidance literature:

With titanium(IV) oxide; In tetrahydrofuran; at 120 ℃; for 16h; under 2250.23 Torr; chemoselective reaction; Inert atmosphere;

DOI:10.1016/j.mcat.2021.111927

Reference yield:

1-dodecyl alcohol (112-53-8) → pentaethylene glycol mono-n-dodecyl ether (3055-95-6,9015-55-8)

Guidance literature:

Multi-step reaction with 5 steps

1: boron fluorid-acetic acid adduct

2: boron fluorid-acetic acid adduct

3: boron fluorid-acetic acid adduct

4: boron fluorid-acetic acid adduct

5: sodium

With sodium; borontrifluoride acetic acid;

Reference yield:

ethylene glycol mono-n-dodecyl ether (4536-30-5,9015-55-8) → pentaethylene glycol mono-n-dodecyl ether (3055-95-6,9015-55-8)

Guidance literature:

Multi-step reaction with 4 steps

1: boron fluorid-acetic acid adduct

2: boron fluorid-acetic acid adduct

3: boron fluorid-acetic acid adduct

4: sodium

With sodium; borontrifluoride acetic acid;

upstream raw materials:

tetraethylene glycol monododecyl ether

2-chloro-ethanol

1-dodecyl alcohol

ethylene glycol mono-n-dodecyl ether

Downstream raw materials:

(2-{2-[2-(2-Dodecyloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid

C12E5OCH2COOH

Refernces

• 1、 Ballesteros–Soberanas, Jordi,Leyva–Pérez, Antonio,Martínez–Castelló, Aarón,Oliver–Meseguer, Judit,Tejeda–Serrano, María. "Nanotitania catalyzes the chemoselective hydration and alkoxylation of epoxides". . . Retrieved 2021/10/12.
• 2、 -. "Combinatorial synthesis of PEG oligomer libraries". Page/Page column 9. . Retrieved 2010/02/15.