2-Methoxy-cyclohexylaMine

Base Information

• Chemical Name: 2-Methoxy-cyclohexylaMine
• CAS No.: 4342-43-2
• Molecular Formula: C7H15NO
• Molecular Weight: 129.202
• Hs Code.: 2922199090
• Mol file: 4342-43-2.mol

Synonyms:2-Methoxy-cyclohexylamine;2-Methoxycyclohexanamine;Cyclohexanamine,2-methoxy;2-Methoxy-cyclohexylamin;

Chemical Property of 2-Methoxy-cyclohexylaMine

Chemical Property:

• PSA: 35.25000
• LogP: 1.60300
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

95-99% ^*data from raw suppliers

2-methoxycyclohexan-1-amine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methoxy-cyclohexylaMine

There total 8 articles about 2-Methoxy-cyclohexylaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.2%

C14H19NO → 2-methoxycyclohexanamine (4342-43-2,742042-55-3)

Guidance literature:

C₁₄H₁₉NO; With hydrogenchloride; In toluene; at -10 - 0 ℃; for 12h;

With sodium hydroxide; In ethanol; at -5 - 0 ℃; for 12h;

Reference yield:

2-Nitroanisole (91-23-6) → 2-methoxycyclohexanamine (4342-43-2,742042-55-3) + 2-methoxy-phenylamine (90-04-0)

Guidance literature:

With hydrogen; In ethanol; at 100 ℃; for 10h; under 22502.3 Torr; Autoclave;

DOI:10.1016/j.apcata.2020.117536

Reference yield:

2-methoxyacetanilide (93-26-5) → 2-methoxycyclohexanamine (4342-43-2,742042-55-3)

Guidance literature:

With ethanol; nickel; at 180 ℃; Hydrogenation.beim Behandeln des danach isolierten N-<2-Methyoxy-cyclohexyl>-acetamids mit wss. Salzsaeure oder wss. Schwefelsaeure;

upstream raw materials:

2-methoxyacetanilide

2-methoxy-phenylamine

2-methoxycyclohexanone

2-aminocyclohexanol

Downstream raw materials:

1-(3-fluoro-4-hydroxy-benzyl)-3-(2-methoxy-cyclohexyl)-urea

Refernces

• 1、 -. "Method for preparing amino ether compounds". . . Retrieved 2017/08/26.
• 2、 -. "CB1 MODULATOR COMPOUNDS". Page/Page column 62. . Retrieved 2008/06/13.