Succinic dihydrazide

Base Information

• Chemical Name: Succinic dihydrazide
• CAS No.: 4146-43-4
• Molecular Formula: C4H10N4O2
• Molecular Weight: 146.149
• Hs Code.: 29280000
• European Community (EC) Number: 223-970-9
• NSC Number: 42940,29540,25180
• UNII: H3WMY7S4LO
• DSSTox Substance ID: DTXSID10194363
• Nikkaji Number: J36.624B
• Wikidata: Q72513775
• ChEMBL ID: CHEMBL3091861
• Mol file: 4146-43-4.mol

Synonyms:succinic dihydrazide

Chemical Property of Succinic dihydrazide

Chemical Property:

• Melting Point: 170-171 °C(lit.)
• Boiling Point: 540.2 °C at 760 mmHg
• PKA: 12.62±0.35(Predicted)
• Flash Point: 280.5 °C
• PSA: 110.24000
• Density: 1.284 g/cm³
• LogP: -0.07120
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Water Solubility.: Soluble in water
• XLogP3: -2.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 146.08037557
• Heavy Atom Count: 10
• Complexity: 119

Purity/Quality:

99% ^*data from raw suppliers

Succinohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(=O)NN)C(=O)NN

Technology Process of Succinic dihydrazide

There total 14 articles about Succinic dihydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

succinic acid diethyl ester (123-25-1) → succinic acid dihydrazide (4146-43-4)

Guidance literature:

With hydrazine hydrate; In methanol; for 8h; Reflux;

DOI:10.1002/anie.201604093

Reference yield: 96.0%

Dimethyl succinate (106-65-0) → succinic acid dihydrazide (4146-43-4)

Guidance literature:

With hydrazine hydrate; In di-isopropyl ether; for 24h; Ambient temperature;

DOI:10.1055/s-1993-25848

Reference yield:

succinic acid anhydride (108-30-5) → succinic acid dihydrazide (4146-43-4)

Guidance literature:

With ethanol; hydrazine hydrate;

DOI:10.1021/ja01154a068

upstream raw materials:

Succinimide

succinic acid anhydride

succinic acid diethyl ester

succinic acid

Downstream raw materials:

succinoyl dichloride

C₁₈H₃₂N₆O₂S₂

1,8-Dibenzoylsuccinohydrazid

4,4'-di(p-anisyl) bis succinyl thiosemicarbazide

Refernces

• 1、 Ahmed, Aziz,Chanu, Oinam B.,Koch, Angira,Lal. "Synthesis, spectroscopic and electrochemical characterisation of binuclear dioxomolybdenum complexes derived from disalicylaldehyde succinoyldihydrazone". . p. 161 - 168. Retrieved 2012.
• 2、 Kruger, Paul E.,Wilson, Benjamin H.. "Supramolecular interactions in a family of dinuclear helicates in the solid-state". . p. 1 - 10. Retrieved 2020.
• 3、 Lal, Ram A.,Chakrabarty, Mithun,Choudhury, Sanjesh,Ahmed, Aziz,Borthakur, Roshmita,Kumar, Arvind. "Synthesis and spectral characterization of homobimetallic molybdenum(VI) complexes derived from bis(2-hydroxy-1-naphthaldehyde)succinoyldihydrazone". . p. 163 - 175. Retrieved 2010.
• 4、 Kumar, Vivek,Upadhyay, Rishibrind Kumar,Bano, Daraksha,Chandra, Subhash,Kumar, Deepak,Jit, Satyabrata,Hasan, Syed Hadi. "The fabrication and characterization of a supramolecular Cu-based metallogel thin-film based Schottky diode". . p. 6273 - 6280. Retrieved 2021/04/16.