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CAS No.: | 4146-43-4 |
---|---|
Name: | Butanedihydrazide |
Article Data: | 30 |
Molecular Structure: | |
Formula: | C4H10N4O2 |
Molecular Weight: | 146.149 |
Synonyms: | Butanedioicacid, dihydrazide (9CI);Succinic acid, dihydrazide (6CI,7CI,8CI);NSC 25180;NSC 29540;NSC 42940;Succinhydrazide;Succinic acid, hydrazide;Succinicdihydrazide;Succinoyldihydrazine;Succinyl dihydrazide; |
EINECS: | 223-970-9 |
Density: | 1.284 g/cm3 |
Melting Point: | 170-171 °C(lit.) |
Boiling Point: | 540.2 °C at 760 mmHg |
Flash Point: | 280.5 °C |
Solubility: | Soluble in water |
Hazard Symbols: | Xn |
Risk Codes: | 22 |
PSA: | 110.24000 |
LogP: | -0.07120 |
Conditions | Yield |
---|---|
With hydrazine hydrate In methanol for 8h; Reflux; | 98% |
With hydrazine hydrate In ethanol for 12h; Reflux; | 65% |
With ethanol; hydrazine hydrate |
Conditions | Yield |
---|---|
With hydrazine hydrate In di-isopropyl ether for 24h; Ambient temperature; | 96% |
With hydrazine hydrate In methanol at 20℃; | 75% |
With hydrazine hydrate In methanol at 20℃; | 69% |
Conditions | Yield |
---|---|
With ethanol; hydrazine hydrate |
Conditions | Yield |
---|---|
With ethanol; hydrazine hydrate | |
With hydrazine hydrate |
succinic acid dihydrazide
Conditions | Yield |
---|---|
With ethanol; hydrazine hydrate |
Conditions | Yield |
---|---|
With hydrazine hydrate Heating; |
2,2'-ethanediylidene-bis-oxazolidine-4,5-dione
succinic acid dihydrazide
Conditions | Yield |
---|---|
With hydrazine hydrate In ethanol Heating; |
The Butanedihydrazide is an organic compound with the formula C4H10N4O2. The IUPAC name of this chemical is butanedihydrazide. With the CAS registry number 4146-43-4, it is also named as Succinic Dihydrazide. The product's categories are Carbonyl Compounds; Hydrazides; Organic Building Blocks. Besides, it should be stored in a dark, cool, dry place at room temperature.
Physical properties about Butanedihydrazide are: (1)ACD/LogP: -3.18; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -3.19; (4)ACD/LogD (pH 7.4): -3.18; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 6; (10)#H bond donors: 6; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 47.1 Å2; (13)Index of Refraction: 1.525; (14)Molar Refractivity: 34.89 cm3; (15)Molar Volume: 113.7 cm3; (16)Polarizability: 13.83×10-24cm3; (17)Surface Tension: 59 dyne/cm; (18)Density: 1.284 g/cm3; (19)Flash Point: 280.5 °C; (20)Enthalpy of Vaporization: 81.78 kJ/mol; (21)Boiling Point: 540.2 °C at 760 mmHg; (22)Vapour Pressure: 9.79E-12 mmHg at 25°C.
Uses of Butanedihydrazide: it can be used to produce 4,4'-dibenzyl bis succinyl thiosemicarbazide by heating. It will need solvent methanol with reaction time of 4 hours. The yield is about 86.5%.
You can still convert the following datas into molecular structure:
(1)SMILES: O=C(NN)CCC(=O)NN
(2)InChI: InChI=1/C4H10N4O2/c5-7-3(9)1-2-4(10)8-6/h1-2,5-6H2,(H,7,9)(H,8,10)
(3)InChIKey: HCOMFAYPHBFMKU-UHFFFAOYAZ
(4)Std. InChI: InChI=1S/C4H10N4O2/c5-7-3(9)1-2-4(10)8-6/h1-2,5-6H2,(H,7,9)(H,8,10)
(5)Std. InChIKey: HCOMFAYPHBFMKU-UHFFFAOYSA-N
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | > 1gm/kg (1000mg/kg) | Journal of Medicinal and Pharmaceutical Chemistry. Vol. 4, Pg. 259, 1961. |