C₃₄H₃₉N₃O₅

Base Information

• Chemical Name: C₃₄H₃₉N₃O₅
• CAS No.: 1390666-38-2
• Molecular Formula: C₃₄H₃₉N₃O₅
• Molecular Weight: 569.701
• Mol file: 1390666-38-2.mol

Synonyms:C₃₄H₃₉N₃O₅

Chemical Property of C₃₄H₃₉N₃O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₃₉N₃O₅

There total 6 articles about C₃₄H₃₉N₃O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

[3-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]boronic acid (913836-04-1) + C25H32BrNO4 (1390665-75-4) → C34H39N3O5 (1390666-38-2)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 8h; Inert atmosphere;

DOI:10.1016/j.bmcl.2012.05.124

Reference yield:

3-(5-ethoxycarbonylpentyloxy)benzaldehyde (1234918-43-4) → C34H39N3O5 (1390666-38-2)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogenchloride / water; toluene / Reflux

2: sodium cyanoborohydride / ethanol / 20 °C / Cooling with ice

3: dmap; triethylamine / dichloromethane / 12 h / 20 °C / Cooling with ice

4: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / N,N-dimethyl-formamide / 8 h / 60 °C / Inert atmosphere

With hydrogenchloride; dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium cyanoborohydride; sodium carbonate; triethylamine; In ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; 4: Suzuki coupling;

DOI:10.1016/j.bmcl.2012.05.124

Reference yield:

C18H29NO3 (1390665-79-8) → C34H39N3O5 (1390666-38-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; triethylamine / dichloromethane / 12 h / 20 °C / Cooling with ice

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / N,N-dimethyl-formamide / 8 h / 60 °C / Inert atmosphere

With dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide; 2: Suzuki coupling;

DOI:10.1016/j.bmcl.2012.05.124

upstream raw materials:

3-(5-ethoxycarbonylpentyloxy)benzaldehyde

[3-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]boronic acid

C₂₅H₃₂BrNO₄

C₁₈H₂₉NO₃

Downstream raw materials:

C₃₂H₃₅N₃O₅

Refernces