Zincacetate

Base Information

• Chemical Name: Zincacetate
• CAS No.: 557-34-6
• Molecular Formula: C4H6O4Zn
• Molecular Weight: 631.827
• Hs Code.: 29152990
• European Community (EC) Number: 209-170-2
• UN Number: 3077
• NCI Thesaurus Code: C47787
• RXCUI: 58295
• Wikipedia: Zinc_acetate
• Mol file: 557-34-6.mol

Synonyms:Anhydrous Zinc Acetate;Galzin;Zinc Acetate;Zinc Acetate Anhydrous;Zinc Acetate Dihydrate;Zinc Acetate, Anhydrous

Chemical Property of Zincacetate

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 13.9mmHg at 25°C
• Melting Point: 83-86 °C
• Boiling Point: 117.1 °C at 760 mmHg
• PKA: 4.756[at 20 ℃]
• Flash Point: 40 °C
• PSA: 37.30000
• Density: 1.84
• LogP: 0.08840
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Water Solubility.: Soluble in water, alcohol, dilute mineral acids and alkalies.
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 183.971401
• Heavy Atom Count: 9
• Complexity: 78.6

Purity/Quality:

99% ^*data from raw suppliers

Zinc acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N,Xi,F
• Hazard Codes: Xn,N,Xi,F
• Statements: 36-50/53-22-11
• Safety Statements: 26-60-61-39-16-7

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Organic Acids, Metal Salts
• Canonical SMILES: CC(=O)O.CC(=O)O.[Zn]
• Recent ClinicalTrials: Effect of Zinc on Glucose Homeostasis
• Recent EU Clinical Trials: Efficacy of zinc on human gut copper uptake depending on zinc type and dose regimen quantified with 64CuCl2 PET/CT-scan
• Recent NIPH Clinical Trials: Clinical study of the preventive effect of Nobelzin on the development of severe oral mucositis during radiation chemotherapy in oral cancer
• Description: Zinc acetate (chemical formula: Zn(O2CCH3)2) is a kind of salt commonly existing in the dihydrate form. It appears as colorless solid. It is produced through the reaction between zinc oxide with acetate acid. Given that zinc is an essential element for growth and development of human body, zinc acetate can be used as a dietary supplement for the treatment of zinc deficiency. It plays an important role for the synthesis of cholesterol, protein, and fats. It can also be used as an astringent, styptic and emetic. In industry, it has various kinds of applications including wood preservation, manufacturing of other zinc salts as well as ethylene acetate, being used as a dye mordant, and analytical reagent.
• Physical properties: The acetate group is capable of binding to metal ions in a variety of ways through its two oxygen atoms and several connectivities are observed for the various hydrates of zinc acetate. Anhydrous zinc acetate adopts a polymeric structure consisting of zinc coordinated to four oxygen atoms in a tetrahedral environment, each tetrahedron being connected to neighbors by the acetate groups . The acetate ligands are not bidentate. In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups. In zinc acetate dihydrate the zinc is octahedral, wherein both acetate groups are bidentate. 2 - 5 - Heating pad Heating Zn(CH3CO2)2 in a vacuum results in loss of acetic anhydride, leaving a residue of ""basic zinc acetate,"" with the formula Zn4O(CH3CO2)6. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ～1.97 vs ～1.63 ? for Be4O(OAc)6.
• Uses: Zinc acetate anhydrous is used in the synthesis of layered Zn-arylphosphonates with potential application in sorption, ion exchange or catalysis. It is utilized in the ultrasonic preparation of zinc sulfide nanoparticles coated on silica particles. It is administered orally or parenterally as a nutritional supplement. It finds an application in the field of industries such as wood preservation, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. It also acts as a plating inhibitor on primary water piping.

Technology Process of Zincacetate

There total 71 articles about Zincacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Allyl acetate (591-87-7) + phenylzinc chloride (28557-00-8) → allylbenzene (300-57-2,57807-91-7) + biphenyl (92-52-4,1594-86-1) + zinc diacetate (557-34-6)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; Ar atmosphere; stirring (20°C, 5 mole-% catalyst, 5 h);

DOI:10.1007/BF00959210

Reference yield: 99.0%

diethylzinc (557-20-0) → zinc diacetate (557-34-6)

Guidance literature:

With acetic acid; In diethyl ether; N2 atmosphere; dropwise addn. of CH3COOH in Et2O to soln. of ZnEt2 (molar ratio Zn/acid 1:2), pptn.; filtration off, washing (Et2O), drying (vac.);

Reference yield: 95.0%

6-bromopyridine-2-carbaldehyde oxime + acetic acid (64-19-7,77671-22-8) + zinc (7440-66-6) → 6-(bromopyridin-2-yl)methanammonium acetate + zinc diacetate (557-34-6)

Guidance literature:

at 20 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/acs.joc.6b02928

upstream raw materials:

acetic anhydride

acetic acid

carbon disulfide

N-nitrosoacetanilide

Downstream raw materials:

4,7-dimethyl-2-phenyl-indole

trimethylsilyl acetate

dicyanozinc

1,2-bis(p-tolylthio)ethane

Refernces

• 1、 Wu, Dapeng,Gao, Zhiyong,Xu, Fang,Chang, Jiuli,Tao, Wenguang,He, Jinjin,Gao, Shuyan,Jiang, Kai. "Hierarchical ZnO aggregates assembled by orderly aligned nanorods for dye-sensitized solar cells". . p. 1210 - 1217. Retrieved 2013.
• 2、 Hu, Xiulan,Masuda, Yoshitake,Ohji, Tatsuki,Kato, Kazumi. "Fabrication of Zn(OH)2/ZnO nanosheet-ZnO nanoarray hybrid structured films by a dissolution-recrystallization Route". . p. 881 - 886. Retrieved 2010.
• 3、 Moezzi, Amir,Cortie, Michael B.,Shimmon, Ronald,McDonagh, Andrew M.. "On the reactivity of zinc hydroxide acetate dihydrate in ethanol". . p. 5133 - 5137. Retrieved 2013.
• 4、 Berezin,Mis'ko,Antina,Berezin. "Stability of nonplanar N-methylporphyrins and their zinc complexes". . p. 482 - 487. Retrieved 2006.
• 5、 Felices, Leire San,Escudero-Adan, Eduardo C.,Benet-Buchholz, Jordi,Kleij, Arjan W.. "Isolation and structural characterization of a binuclear intermediate species pertinent to transmetalation of Zn(salphen) complexes and the formation of polynuclear salen structures". . p. 846 - 853. Retrieved 2009.
• 6、 Hardt,Stavenow. "". . p. 267. Retrieved 1959.
• 7、 Paul, A.,Acharya, H. N.. "". . . Retrieved 1992.
• 8、 -. "Radiation-sensitive composition, pattern-forming method and radiation-sensitive acid generating agent". . . Retrieved 2021/12/31.
• 9、 Swiatkowski, Marcin,Kruszynski, Rafal. "Structurally diverse coordination compounds of zinc as effective precursors of zinc oxide nanoparticles with various morphologies". . . Retrieved 2019/04/01.