L-GLUTAMIC ACID, MONOAMMONIUM SALT

Base Information

• Chemical Name: L-GLUTAMIC ACID, MONOAMMONIUM SALT
• CAS No.: 7558-63-6
• Molecular Formula: C5H9 N O4 . H3 N
• Molecular Weight: 164.161
• Hs Code.: 2923900090
• Mol file: 7558-63-6.mol

Synonyms:Glutamicacid, monoammonium salt, L- (8CI); L-Glutamic acid, monoammonium salt (9CI);Ammonium glutamate; E 624; Glutamic acid monoammonium salt; MonoammoniumL-glutamate; Monoammonium glutamate

Chemical Property of L-GLUTAMIC ACID, MONOAMMONIUM SALT

Chemical Property:

• PSA: 103.86000
• LogP: 0.28730
• Storage Temp.: −20°C
• Solubility.: Aqueous Acid (Slightly), Methanol (Very Slightly), Water (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

MAG ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Description: Refer to monosodium glutamate. L-Glutamic acid is a non-essential amino acid and the primary excitatory neurotransmitter in the CNS. It acts on ionotropic and metabotropic receptors to induce excitatory synaptic transmission and has roles in synaptic plasticity. Excessive release of L-glutamic acid induces excitotoxicity that is associated with various human diseases, including amyotrophic lateral sclerosis (ALS), stroke, Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease. Excessive L-glutamic acid release, in its protonated glutamate form, also occurs during seizure activity and contributes to epileptogenesis and seizure-induced brain damage.
• Uses: L-Glutamic Acid Monoammonium Salt is a food additive; It can protect hypertensive rats from strokes. Monoammonium l-Glutamate is a flavor enhancer and salt substitute that is crystalline powder (white, free-flowing) and odorless. It is soluble in water, insoluble in common organic solvents, and is obtained by chemical synthesis. It is a low sodium alternative to monosodium glutamate. It is used in meats, soups, gravies, and sausage. It is also termed ammonium glutamate and monoammonium glutamate.

Technology Process of L-GLUTAMIC ACID, MONOAMMONIUM SALT

There total 3 articles about L-GLUTAMIC ACID, MONOAMMONIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-glutamine (56-85-9,26700-71-0) → L-glutamate (7558-63-6)

Guidance literature:

With L-glutamate dehydrogenase; at 30 ℃; for 0.166667h; aq. phosphate buffer;

DOI:10.1111/j.1742-4658.2009.07523.x

Reference yield:

L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) → L-glutamate (7558-63-6)

Guidance literature:

Reference yield:

N-phthaloyl-L-glutamic acid (340-90-9,2301-52-2) → (S)-2-Amino-pentanedioic acid; compound with ammonia (7558-63-6,10366-72-0,15673-81-1,17140-86-2,20806-32-0,25677-11-6)

Guidance literature:

With sodium tetrahydroborate; acetic acid; deprotection; 1.) 2-propanol, water, 24 h, 2.) 80 deg C, 2 h;

DOI:10.1016/S0040-4039(01)81169-2

upstream raw materials:

N-phthaloyl-L-glutamic acid

L-glutamic acid

L-glutamine

Downstream raw materials:

L-glutamic acid dipropyl ester

Refernces

• 1、 Osby, John O.,Martin, Michael G.,Ganem, Bruce. "AN EXCEPTIONALLY MILD DEPROTECTION OF PHTHALIMIDES". . p. 2093 - 2096. Retrieved 2007/10/02.