Tolylfluanid

Base Information

• Chemical Name: Tolylfluanid
• CAS No.: 731-27-1
• Molecular Formula: C10H13 Cl2 F N2 O2 S2
• Molecular Weight: 347.262
• European Community (EC) Number: 211-986-9
• UNII: 382277YXSG
• DSSTox Substance ID: DTXSID8042478
• Nikkaji Number: J6.957D
• Wikipedia: Tolylfluanid
• Wikidata: Q423824
• ChEMBL ID: CHEMBL3189057
• Mol file: 731-27-1.mol

Synonyms:Euparen M;N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide;tolyfluanid;tolylfluanid

Chemical Property of Tolylfluanid

Chemical Property:

• Vapor Pressure: 1.51E-05mmHg at 25°C
• Melting Point: 96°C
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 366oC at 760 mmHg
• PKA: -5.06±0.50(Predicted)
• Flash Point: 175.1oC
• PSA: 74.30000
• Density: 1.505g/cm3
• LogP: 4.39520
• Storage Temp.: 0-6°C
• Water Solubility.: 0.9 mg l-1 (20 °C)
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 345.9779536
• Heavy Atom Count: 19
• Complexity: 393

Purity/Quality:

99.9% ^*data from raw suppliers

Tolylfluanide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,N
• Hazard Codes: T,N,T+
• Statements: 23-36/37/38-43-48/20-50/53-50-48/23-26
• Safety Statements: 24-26-37-38-45-60-61-63-36/37/39-28

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Fungicides
• Canonical SMILES: CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C
• Uses: Tolylfluanid is used to control a wide range of fungal diseases on apples, grapes, strawberries and other fruit and storage diseases on many crops. Tolylfluanid may be used as a reference standard for the determination of the analyte in nutraceutical formulations using dispersive liquid-liquid microextraction(DLLME) coupled with gas chromatography-mass spectrometry method.

Technology Process of Tolylfluanid

There total 3 articles about Tolylfluanid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-N'-(4-methylphenyl)-sulfamide (66840-71-9) + dichlorofluoromethanesulphenyl chloride (2712-93-8) → dichloro-N-[(dimethylamino)sulfonyl]fluoro-N-(p-tolyl)methanesulfenamide (731-27-1)

Guidance literature:

N,N-dimethyl-N'-(4-methylphenyl)-sulfamide; With sodium hydride; In tetrahydrofuran; at 0 - 10 ℃; Inert atmosphere;

dichlorofluoromethanesulphenyl chloride; In tetrahydrofuran; at 20 ℃; Reagent/catalyst; Temperature; Inert atmosphere;

Reference yield:

N,N-dimethyl-N'-(4-methylphenyl)-sulfamide (66840-71-9) + triethylamine (121-44-8) + dichlorofluoromethanesulphenyl chloride (2712-93-8) → dichloro-N-[(dimethylamino)sulfonyl]fluoro-N-(p-tolyl)methanesulfenamide (731-27-1)

Guidance literature:

Reference yield:

→ dichloro-N-[(dimethylamino)sulfonyl]fluoro-N-(p-tolyl)methanesulfenamide (731-27-1)

Guidance literature:

upstream raw materials:

N,N-dimethyl-N'-(4-methylphenyl)-sulfamide

triethylamine

dichlorofluoromethanesulphenyl chloride

Downstream raw materials:

methylamine

Refernces

• 1、 -. "Synergistic Combinations Of Active Ingredients". . . Retrieved 2012/02/15.
• 2、 -. "ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES". . . Retrieved 2010/08/18.